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Pedro De-la-Torre
Pedro De-la-Torre
Research Scientist, Massachusetts Eye and Ear, Department of Otolaryngology, Harvard Medical School
Verified email at meei.harvard.edu - Homepage
Title
Cited by
Cited by
Year
A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles
P de la Torre, LA Saavedra, J Caballero, J Quiroga, JH Alzate-Morales, ...
Molecules 17 (10), 12072-12085, 2012
482012
Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness
A Jaiganesh, P De-la-Torre, AA Patel, DJ Termine, F Velez-Cortes, ...
Structure, 2018
452018
Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception
D Choudhary, Y Narui, BL Neel, LN Wimalasena, CF Klanseck, ...
Proceedings of the National Academy of Sciences 117 (40), 24837-24848, 2020
372020
Design, facile synthesis, and evaluation of novel spiro-and pyrazolo [1, 5-c] quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies
J Gálvez, S Polo, B Insuasty, M Gutiérrez, D Cáceres, JH Alzate-Morales, ...
Computational biology and chemistry 74, 218-229, 2018
372018
A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15
P De-la-Torre, D Choudhary, R Araya-Secchi, Y Narui, M Sotomayor
Biophysical journal 115 (12), 2368-2385, 2018
292018
Ultrasound-assisted phase-transfer catalysis method in an aqueous medium to promote the Knoevenagel reaction: Advantages over the conventional and microwave-assisted solvent …
P De-la-Torre, E Osorio, JH Alzate-Morales, J Caballero, J Trilleras, ...
Ultrasonics sonochemistry 21 (5), 1666-1674, 2014
152014
Synthesis and in silico analysis of the quantitative structure–activity relationship of heteroaryl–acrylonitriles as AChE inhibitors
P De-la-Torre, AV Treuer, M Gutierrez, H Poblete, JH Alzate-Morales, ...
Journal of the Taiwan Institute of Chemical Engineers 59, 45-60, 2016
142016
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F
MV Ivanchenko, DM Hathaway, AJ Klein, B Pan, O Strelkova, ...
Nature Communications 14 (1), 2400, 2023
112023
Solvent-free microwave-assisted synthesis of substituted pyridines using NH4OAc as nitrogen source
J Trilleras, P De La Torre, D J. Pacheco, J Quiroga, M Nogueras, J Cobo
Letters in Organic Chemistry 8 (9), 652, 2011
112011
Mechanism study of the thiol-addition reaction to benzothiazole derivative for sensing endogenous thiols
O García-Beltrán, JG Santos, S Fuentealba, P De la Torre, P Pavez, ...
Tetrahedron Letters 56 (19), 2437-2440, 2015
102015
5-(Indol-2-yl) pyrazolo [3, 4-b] pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis
D Ramírez, M Mejia-Gutierrez, B Insuasty, S Rinné, AK Kiper, M Platzk, ...
Molecules 26 (13), 3897, 2021
82021
(E)-2-(Benzo [d] thiazol-2-yl)-3-heteroarylacrylonitriles as efficient Michael acceptors for cysteine: Real application in biological imaging
P De la Torre, O García-Beltrán, W Tiznado, N Mena, LA Saavedra, ...
Sensors and Actuators B: Chemical 193, 391-399, 2014
82014
Optimal graph‐based and Simplified Molecular Input Line Entry System‐based descriptors for quantitative structure–activity relationship analysis of arylalkylaminoalcohols …
L Quesada‐Romero, K Mena‐Ulecia, M Zuñiga, P De‐la‐Torre, D Rossi, ...
Journal of Chemometrics 29 (1), 13-20, 2015
72015
Structural determinants of protocadherin-15 elasticity and function in inner-ear mechanotransduction
D Choudhary, Y Narui, BL Neel, LN Wimalasena, CF Klanseck, ...
bioRxiv, 695502, 2019
32019
Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation
AV Treuer, P De-La-Torre, MI Gutiérrez
Journal of Chemistry 2017, 2017
32017
Structuring Inner-ear Mechanotransduction
D Choudhary, Y Narui, B Neel, S Walujkar, JM Lotthammer, JC Sudar, ...
Biophysical Journal 118 (3), 13a, 2020
12020
Structures and Simulations of Membrane Adjacent Fragments of Protocadherin-15
P De-la-Torre, Y Narui, D Choudhary, R Araya-Secchi, M Sotomayor
Biophysical Journal 116 (3), 459a, 2019
12019
PKHD1L1, A Gene Involved in the Stereocilia Coat, Causes Autosomal Recessive Nonsyndromic Hearing Loss
SE Redfield, P De-la-Torre, M Zamani, H Wang, H Khan, T Morris, ...
Human Genetics 09 March 2024, 2024
2024
PKHD1L1 is Required for Stereocilia Bundle Maintenance, Prolonged Hearing Function and Enhanced Resilience to Noise Exposure
OS Strelkova, RT Osgood, CJ Tian, X Zhang, E Hale, P De-la-Torre, ...
bioRxiv, 2024
2024
In silico mechanics of mini-PCDH15 proteins rationally designed for inner-ear gene therapy
H Wen, P De-la-Torre, K Martínez-Pérez, J Brower, Y Narui, M Ivanchenko, ...
Biophysical Journal 123 (3), 201a, 2024
2024
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