The ageing systemic milieu negatively regulates neurogenesis and cognitive function SA Villeda, J Luo, KI Mosher, B Zou, M Britschgi, G Bieri, TM Stan, ... Nature 477 (7362), 90-94, 2011 | 1837 | 2011 |
β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis LK Smith, Y He, JS Park, G Bieri, CE Snethlage, K Lin, G Gontier, R Wabl, ... Nature medicine 21 (8), 932-937, 2015 | 453 | 2015 |
NADPH oxidase–independent formation of extracellular DNA traps by basophils M Morshed, R Hlushchuk, D Simon, AF Walls, K Obata-Ninomiya, ... The Journal of Immunology 192 (11), 5314-5323, 2014 | 180 | 2014 |
The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab P Gasser, SS Tarchevskaya, P Guntern, D Brigger, R Ruppli, N Zbären, ... Nature communications 11 (1), 165, 2020 | 154 | 2020 |
Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells A Eggel, G Baravalle, G Hobi, B Kim, P Buschor, P Forrer, JS Shin, ... Journal of allergy and clinical immunology 133 (6), 1709-1719. e8, 2014 | 154 | 2014 |
Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor B Kim, A Eggel, SS Tarchevskaya, M Vogel, H Prinz, TS Jardetzky Nature 491 (7425), 613-617, 2012 | 108 | 2012 |
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ... Nature communications 7 (1), 11610, 2016 | 106 | 2016 |
A revival of parabiosis in biomedical research A Eggel, T Wyss-Coray Swiss medical weekly 144 (0506), w13914-w13914, 2014 | 84 | 2014 |
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age D Brigger, C Riether, R van Brummelen, KI Mosher, A Shiu, Z Ding, ... Nature metabolism 2 (8), 688-702, 2020 | 79 | 2020 |
DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage A Eggel, MJ Baumann, P Amstutz, BM Stadler, M Vogel Journal of molecular biology 393 (3), 598-607, 2009 | 70 | 2009 |
Inhibition of ongoing allergic reactions using a novel anti‐IgE DARPin‐Fc fusion protein A Eggel, P Buschor, MJ Baumann, P Amstutz, BM Stadler, M Vogel Allergy 66 (7), 961-968, 2011 | 61 | 2011 |
Past, present, and future of anti‐IgE biologics P Guntern, A Eggel Allergy 75 (10), 2491-2502, 2020 | 57 | 2020 |
DARPins against a functional IgE epitope MJ Baumann, A Eggel, P Amstutz, BM Stadler, M Vogel Immunology letters 133 (2), 78-84, 2010 | 54 | 2010 |
A novel bispecific DARP in targeting Fcγ RIIB and Fcε RI‐bound IgE inhibits allergic responses F Zellweger, P Gasser, D Brigger, P Buschor, M Vogel, A Eggel Allergy 72 (8), 1174-1183, 2017 | 52 | 2017 |
IgE‐associated allergic disorders: recent advances in etiology, diagnosis, and treatment F Zellweger, A Eggel Allergy 71 (12), 1652-1661, 2016 | 45 | 2016 |
Targeting IgE in allergic disease P Gasser, A Eggel Current opinion in immunology 54, 86-92, 2018 | 40 | 2018 |
Accuracy of serological testing for SARS‐CoV‐2 antibodies: first results of a large mixed‐method evaluation study D Brigger, MP Horn, LF Pennington, AE Powell, D Siegrist, B Weber, ... Allergy 76 (3), 853-865, 2021 | 36 | 2021 |
Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions LF Pennington, P Gasser, D Brigger, P Guntern, A Eggel, TS Jardetzky Journal of Allergy and Clinical Immunology 148 (4), 1049-1060, 2021 | 25 | 2021 |
A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E–receptor interactions B Kim, SS Tarchevskaya, A Eggel, M Vogel, TS Jardetzky Analytical biochemistry 431 (2), 84-89, 2012 | 25 | 2012 |
IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils F Zellweger, P Buschor, G Hobi, D Brigger, CA Dahinden, PM Villiger, ... Cell death & disease 9 (5), 510, 2018 | 24 | 2018 |