Catherine Z Chen
Catherine Z Chen
National Center for Advancing Translational Sciences
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Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
F Jacob, SR Pather, WK Huang, F Zhang, SZH Wong, H Zhou, B Cubitt, ...
Cell stem cell 27 (6), 937-950. e9, 2020
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ...
Emerging microbes & infections 3 (1), 1-7, 2014
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
Q Zhang, CZ Chen, M Swaroop, M Xu, L Wang, J Lee, AQ Wang, ...
Cell discovery 6 (1), 1-14, 2020
Elp1p, the yeast homolog of the FD disease syndrome protein, negatively regulates exocytosis independently of transcriptional elongation
PB Rahl, CZ Chen, RN Collins
Molecular cell 17 (6), 841-853, 2005
Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening
W Zhu, M Xu, CZ Chen, H Guo, M Shen, X Hu, P Shinn, ...
ACS Pharmacology & Translational Science 3 (5), 1008-1016, 2020
Dual prenylation is required for Rab protein localization and function
M Calero, CZ Chen, W Zhu, N Winand, KA Havas, PM Gilbert, CG Burd, ...
Molecular biology of the cell 14 (5), 1852-1867, 2003
RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery
W Zhu, CZ Chen, K Gorshkov, M Xu, DC Lo, W Zheng
SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2472555220942123, 2020
Contrast material travel times in patients undergoing peripheral MR angiography
MR Prince, SG Chabra, R Watts, CZ Chen, PA Winchester, NM Khilnani, ...
Radiology 224 (1), 55-61, 2002
The SARS-CoV-2 cytopathic effect is blocked by lysosome alkalizing small molecules
K Gorshkov, CZ Chen, R Bostwick, L Rasmussen, BN Tran, YS Cheng, ...
ACS infectious diseases 7 (6), 1389-1408, 2020
Synergistic and Antagonistic Drug Combinations against SARS-CoV-2
T Bobrowski, L Chen, RT Eastman, Z Itkin, P Shinn, CZ Chen, H Guo, ...
Molecular Therapy 29 (2), 873-885, 2021
Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles
CZ Chen, M Xu, M Pradhan, K Gorshkov, JD Petersen, MR Straus, W Zhu, ...
ACS Pharmacology & Translational Science 3 (6), 1165-1175, 2020
Drug discovery strategies for SARS-CoV-2
ZA Shyr, K Gorshkov, CZ Chen, W Zheng
Journal of Pharmacology and Experimental Therapeutics 375 (1), 127-138, 2020
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules
JL Childs-Disney, E Stepniak-Konieczna, T Tran, I Yildirim, HJ Park, ...
Nature communications 4 (1), 1-11, 2013
Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p
S Buvelot Frei, PB Rahl, M Nussbaum, BJ Briggs, M Calero, S Janeczko, ...
Molecular and cellular biology 26 (19), 7299-7317, 2006
A role for Yip1p in COPII vesicle biogenesis
M Heidtman, CZ Chen, RN Collins, C Barlowe
The Journal of cell biology 163 (1), 57-69, 2003
Drug repurposing screen for compounds inhibiting the cytopathic effect of SARS-CoV-2
CZ Chen, P Shinn, Z Itkin, RT Eastman, R Bostwick, L Rasmussen, ...
Frontiers in Pharmacology 11, 2020
An OpenData portal to share COVID-19 drug repurposing data in real time
KR Brimacombe, T Zhao, RT Eastman, X Hu, K Wang, M Backus, ...
bioRxiv, 2020
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic …
A Ketley, CZ Chen, X Li, S Arya, TE Robinson, J Granados-Riveron, ...
Human molecular genetics 23 (6), 1551-1562, 2014
Bolus arterial-venous transit in the lower extremity and venous contamination in bolus chase three-dimensional magnetic resonance angiography
Y Wang, CZ Chen, SG Chabra, PA Winchester, NM Khilnani, R Watts, ...
Investigative radiology 37 (8), 458-463, 2002
Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1
J Xiao, Z Huang, CZ Chen, IU Agoulnik, N Southall, X Hu, RE Jones, ...
Nature communications 4 (1), 1-7, 2013
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Artículos 1–20