Jeffery Klco
Jeffery Klco
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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
The origin and evolution of mutations in acute myeloid leukemia
JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ...
Cell 150 (2), 264-278, 2012
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
K Kondo, J Klco, E Nakamura, M Lechpammer, WG Kaelin Jr
Cancer cell 1 (3), 237-246, 2002
Suppression of tumor growth through disruption of hypoxia-inducible transcription
AL Kung, S Wang, JM Klco, WG Kaelin, DM Livingston
Nature medicine 6 (12), 1335-1340, 2000
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ...
Nature 518 (7540), 552-555, 2015
von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF
MA Hoffman, M Ohh, H Yang, JM Klco, M Ivan, WG Kaelin Jr
Human molecular genetics 10 (10), 1019-1027, 2001
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia
JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ...
Cancer cell 25 (3), 379-392, 2014
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia
JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ...
Jama 314 (8), 811-822, 2015
Use of whole-genome sequencing to diagnose a cryptic fusion oncogene
JS Welch, P Westervelt, L Ding, DE Larson, JM Klco, S Kulkarni, J Wallis, ...
Jama 305 (15), 1577-1584, 2011
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
BZ Olenyuk, GJ Zhang, JM Klco, NG Nickols, WG Kaelin Jr, PB Dervan
Proceedings of the National Academy of Sciences 101 (48), 16768-16773, 2004
Immune escape of relapsed AML cells after allogeneic transplantation
MJ Christopher, AA Petti, MP Rettig, CA Miller, E Chendamarai, ...
New England Journal of Medicine 379 (24), 2330-2341, 2018
pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development
NH Stickle, J Chung, JM Klco, RP Hill, WG Kaelin Jr, M Ohh
Molecular and cellular biology 24 (8), 3251-3261, 2004
The genomic landscape of core-binding factor acute myeloid leukemias
ZJ Faber, X Chen, AL Gedman, K Boggs, J Cheng, J Ma, I Radtke, ...
Nature genetics 48 (12), 1551-1556, 2016
Essential role for the second extracellular loop in C5a receptor activation
JM Klco, CB Wiegand, K Narzinski, TJ Baranski
Nature structural & molecular biology 12 (4), 320-326, 2005
Optimizing cancer genome sequencing and analysis
M Griffith, CA Miller, OL Griffith, K Krysiak, ZL Skidmore, A Ramu, ...
Cell systems 1 (3), 210-223, 2015
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways
Y Jiang, W Zhang, K Kondo, JM Klco, TB St. Martin, MR Dufault, ...
Molecular Cancer Research 1 (6), 453-462, 2003
Genomic impact of transient low-dose decitabine treatment on primary AML cells
JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ...
Blood, The Journal of the American Society of Hematology 121 (9), 1633-1643, 2013
C5a Receptor Oligomerization: I. disulfide trapping reveals oligomers and potential contact surfaces in ag protein-coupled receptor
JM Klco, TB Lassere, TJ Baranski
Journal of Biological Chemistry 278 (37), 35345-35353, 2003
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
RKS Malireddi, P Gurung, J Mavuluri, TK Dasari, JM Klco, H Chi, ...
Journal of Experimental Medicine 215 (4), 1023-1034, 2018
The genomic landscape of pediatric myelodysplastic syndromes
JR Schwartz, J Ma, T Lamprecht, M Walsh, S Wang, V Bryant, G Song, ...
Nature communications 8 (1), 1-10, 2017
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Artículos 1–20