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Arjan Boltjes
Arjan Boltjes
Princess Máxima Center for pediatric oncology
Dirección de correo verificada de prinsesmaximacentrum.nl - Página principal
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Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics
MAC Depuydt, KHM Prange, L Slenders, T Örd, D Elbersen, A Boltjes, ...
Circulation research 127 (11), 1437-1455, 2020
3392020
Human dendritic cell functional specialization in steady-state and inflammation
A Boltjes, F Van Wijk
Frontiers in immunology 5, 83079, 2014
2472014
The role of Kupffer cells in hepatitis B and hepatitis C virus infections
A Boltjes, D Movita, A Boonstra, AM Woltman
Journal of hepatology 61 (3), 660-671, 2014
2012014
IFN‐λ‐mediated IL‐12 production in macrophages induces IFN‐γ production in human NK cells
RA de Groen, A Boltjes, J Hou, BS Liu, F McPhee, J Friborg, HLA Janssen, ...
European journal of immunology 45 (1), 250-259, 2015
892015
Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function
A Boltjes, N van Montfoort, PJ Biesta, ML Op den Brouw, J Kwekkeboom, ...
The Journal of infectious diseases 211 (8), 1268-1278, 2015
71*2015
Genetic regulation of atherosclerosis-relevant phenotypes in human vascular smooth muscle cells
R Aherrahrou, L Guo, VP Nagraj, A Aguhob, J Hinkle, L Chen, J Yuhl Soh, ...
Circulation research 127 (12), 1552-1565, 2020
692020
Prosaposin mediates inflammation in atherosclerosis
MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ...
Science translational medicine 13 (584), eabe1433, 2021
492021
Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells
MAC Depuydt, FH Schaftenaar, KHM Prange, A Boltjes, E Hemme, ...
Nature Cardiovascular Research 2 (2), 112-125, 2023
372023
Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis
L Slenders, LPL Landsmeer, K Cui, MAC Depuydt, M Verwer, J Mekke, ...
European heart journal open 2 (1), oeab043, 2022
332022
Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease
A Boltjes, ZM Groothuismink, GW van Oord, HLA Janssen, AM Woltman, ...
PLoS One 9 (5), e97006, 2014
332014
Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’
KPS Langenberg, MT Meister, JJ Bakhuizen, JM Boer, ...
European Journal of Cancer 175, 311-325, 2022
192022
Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation
M Mokry, A Boltjes, L Slenders, G Bel-Bordes, K Cui, E Brouwer, ...
Nature cardiovascular research 1 (12), 1140-1155, 2022
172022
Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients
A Boltjes, MLO den Brouw, PJ Biesta, RS Binda, RG van der Molen, ...
Molecular Immunology 53 (1-2), 72-78, 2013
8*2013
Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition
JGC Peeters, A Boltjes, RC Scholman, SJ Vervoort, PJ Coffer, M Mokry, ...
Rheumatology 62 (8), 2887-2897, 2023
72023
Transcriptomic-based clustering of advanced atherosclerotic plaques identifies subgroups of plaques with differential underlying biology that associate with clinical presentation
M Mokry, A Boltjes, K Cui, L Slenders, JM Mekke, MAC Depuydt, ...
medRxiv, 2021.11. 25.21266855, 2021
62021
Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis
G Mijnheer, NH Servaas, JY Leong, A Boltjes, E Spierings, P Chen, L Lai, ...
Elife 12, e79016, 2023
42023
Conventional dendritic cells type 1 are strongly enriched, quiescent and relatively tolerogenic in local inflammatory arthritis
A Boltjes, AAK Samat, M Plantinga, M Mokry, B Castelijns, JF Swart, ...
Frontiers in Immunology 13, 1101999, 2023
42023
Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women.
R Hartman, M Siemelink, S Haitjema, KF Dekkers, L Slenders, A Boltjes, ...
Atherosclerosis 331, e217, 2021
42021
Plasma testosterone levels and atherosclerotic plaque gene expression in men with advanced atherosclerosis
F Groepenhoff, E Diez Benavente, A Boltjes, N Timmerman, F Waissi, ...
Frontiers in Cardiovascular Medicine 8, 693351, 2021
42021
Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans
D Van Keulen, ID Van Koeverden, A Boltjes, HMG Princen, AJ Van Gool, ...
Frontiers in cardiovascular medicine 8, 658915, 2021
42021
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