WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy D Bakula, AJ Müller, T Zuleger, Z Takacs, M Franz-Wachtel, AK Thost, ... Nature communications 8 (1), 15637, 2017 | 188 | 2017 |
The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab P Gasser, SS Tarchevskaya, P Guntern, D Brigger, R Ruppli, N Zbären, ... Nature communications 11 (1), 165, 2020 | 154 | 2020 |
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ... Nature communications 7 (1), 11610, 2016 | 106 | 2016 |
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age D Brigger, C Riether, R van Brummelen, KI Mosher, A Shiu, Z Ding, ... Nature metabolism 2 (8), 688-702, 2020 | 79 | 2020 |
Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells [S] SG Pfisterer, D Bakula, T Frickey, A Cezanne, D Brigger, MP Tschan, ... Journal of lipid research 55 (7), 1267-1278, 2014 | 65 | 2014 |
p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells A Trocoli, P Bensadoun, E Richard, G Labrunie, F Merhi, AM Schläfli, ... Cell Death & Differentiation 21 (12), 1852-1861, 2014 | 60 | 2014 |
A novel bispecific DARP in targeting Fcγ RIIB and Fcε RI‐bound IgE inhibits allergic responses F Zellweger, P Gasser, D Brigger, P Buschor, M Vogel, A Eggel Allergy 72 (8), 1174-1183, 2017 | 52 | 2017 |
WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells D Brigger, T Proikas-Cezanne, MP Tschan Cell death & disease 5 (7), e1315-e1315, 2014 | 48 | 2014 |
Accuracy of serological testing for SARS‐CoV‐2 antibodies: first results of a large mixed‐method evaluation study D Brigger, MP Horn, LF Pennington, AE Powell, D Siegrist, B Weber, ... Allergy 76 (3), 853-865, 2021 | 36 | 2021 |
Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation D Brigger, BE Torbett, J Chen, MF Fey, MP Tschan Biochemical and biophysical research communications 438 (2), 283-288, 2013 | 34 | 2013 |
Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity D Brigger, AM Schläfli, E Garattini, MP Tschan Cell death & disease 6 (8), e1861-e1861, 2015 | 29 | 2015 |
Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions LF Pennington, P Gasser, D Brigger, P Guntern, A Eggel, TS Jardetzky Journal of Allergy and Clinical Immunology 148 (4), 1049-1060, 2021 | 25 | 2021 |
IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils F Zellweger, P Buschor, G Hobi, D Brigger, CA Dahinden, PM Villiger, ... Cell death & disease 9 (5), 510, 2018 | 24 | 2018 |
Induction of the autophagy-associated gene MAP1S via PU. 1 supports APL differentiation A Haimovici, D Brigger, BE Torbett, MF Fey, MP Tschan Leukemia research 38 (9), 1041-1047, 2014 | 19 | 2014 |
A novel functional mast cell assay for the detection of allergies N Zbären, D Brigger, D Bachmann, A Helbling, L Jörg, MP Horn, ... Journal of Allergy and Clinical Immunology 149 (3), 1018-1030. e11, 2022 | 16 | 2022 |
Serological testing for SARS‐CoV‐2 antibodies in clinical practice: a comparative diagnostic accuracy study MP Horn, HR Jonsdottir, D Brigger, L Damonti, F Suter‐Riniker, O Endrich, ... Allergy 77 (7), 2090-2103, 2022 | 14 | 2022 |
Sex-specific differences in immune response to SARS-CoV-2 vaccination vanish with age. D Brigger, PM Guntern, HR Jonsdottir, LF Pennington, B Weber, ... Allergy 78 (6), 1683-1686, 2023 | 1 | 2023 |
The Disruptive Anti-IgE Molecule KIH_E07_79 Rapidly Desensitizes Allergic Effector Cells and Suppresses IgE Production in B-cells P Guntern, L Pennington, D Brigger, T Jardetzky, A Eggel Journal of Allergy and Clinical Immunology 153 (2), AB63, 2024 | | 2024 |
Fast acting disruptive IgE inhibitors rapidly desensitize allergic effector cells and resolve IgE-mediated anaphylaxis LF Pennington, P Gasser, D Brigger, P Guntern, A Eggel, TS Jardetzky ALLERGY 76, 21-21, 2021 | | 2021 |
COVID-19: angiotensin II in development of lung immunothrombosis and vasculitis mimics–Authors reply D Brigger, MP Horn, LF Pennington, AE Powell, D Siegrist, B Weber, ... Blackwell Publishing Ltd, 2021 | | 2021 |