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Tairan Yuwen
Tairan Yuwen
Dirección de correo verificada de pku.edu.cn
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Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
P Vallurupalli, A Sekhar, T Yuwen, LE Kay
Journal of biomolecular NMR 67, 243-271, 2017
1392017
Slow conformational exchange and overall rocking motion in ubiquitin protein crystals
V Kurauskas, SA Izmailov, ON Rogacheva, A Hessel, I Ayala, ...
Nature communications 8 (1), 145, 2017
822017
Observing the overall rocking motion of a protein in a crystal
P Ma, Y Xue, N Coquelle, JD Haller, T Yuwen, I Ayala, O Mikhailovskii, ...
Nature communications 6 (1), 8361, 2015
752015
Microsecond time-scale conformational exchange in proteins: using long molecular dynamics trajectory to simulate NMR relaxation dispersion data
Y Xue, JM Ward, T Yuwen, IS Podkorytov, NR Skrynnikov
Journal of the American Chemical Society 134 (5), 2555-2562, 2012
702012
Reversible inhibition of the ClpP protease via an N-terminal conformational switch
S Vahidi, ZA Ripstein, M Bonomi, T Yuwen, MF Mabanglo, JB Juravsky, ...
Proceedings of the National Academy of Sciences 115 (28), E6447-E6456, 2018
572018
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
J Kitevski-LeBlanc, A Fradet-Turcotte, P Kukic, MD Wilson, G Portella, ...
Elife 6, e23872, 2017
502017
Role of electrostatic interactions in binding of peptides and intrinsically disordered proteins to their folded targets. 1. NMR and MD characterization of the complex between …
Y Xue, T Yuwen, F Zhu, NR Skrynnikov
Biochemistry 53 (41), 6473-6495, 2014
462014
Investigating the dynamics of destabilized nucleosomes using methyl-TROSY NMR
JL Kitevski-LeBlanc, T Yuwen, PN Dyer, J Rudolph, K Luger, LE Kay
Journal of the American Chemical Society 140 (14), 4774-4777, 2018
452018
Enhancing the Sensitivity of CPMG Relaxation Dispersion to Conformational Exchange Processes by Multiple‐Quantum Spectroscopy
T Yuwen, P Vallurupalli, LE Kay
Angewandte Chemie International Edition 55 (38), 11490-11494, 2016
432016
Dramatic Decrease in CEST Measurement Times Using Multi‐Site Excitation
T Yuwen, LE Kay, G Bouvignies
ChemPhysChem 19 (14), 1707-1710, 2018
392018
Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1H‐CEST
T Yuwen, A Sekhar, LE Kay
Angewandte Chemie International Edition 56 (22), 6122-6125, 2017
382017
Probing Conformational Exchange in Weakly Interacting, Slowly Exchanging Protein Systems via Off-Resonance R Experiments: Application to Studies of …
T Yuwen, JP Brady, LE Kay
Journal of the American Chemical Society 140 (6), 2115-2126, 2018
372018
CP-HISQC: a better version of HSQC experiment for intrinsically disordered proteins under physiological conditions
T Yuwen, NR Skrynnikov
Journal of biomolecular NMR 58, 175-192, 2014
352014
A Methyl‐TROSY‐Based 1H Relaxation Dispersion Experiment for Studies of Conformational Exchange in High Molecular Weight Proteins
T Yuwen, R Huang, P Vallurupalli, LE Kay
Angewandte Chemie 131 (19), 6316-6320, 2019
342019
Proton-decoupled CPMG: A better experiment for measuring 15N R2 relaxation in disordered proteins
T Yuwen, NR Skrynnikov
Journal of Magnetic Resonance 241, 155-169, 2014
302014
Probing slow timescale dynamics in proteins using methyl 1H CEST
T Yuwen, R Huang, LE Kay
Journal of Biomolecular NMR 68, 215-224, 2017
292017
Exploring methods to expedite the recording of CEST datasets using selective pulse excitation
T Yuwen, G Bouvignies, LE Kay
Journal of Magnetic Resonance 292, 1-7, 2018
262018
Measuring Solvent Hydrogen Exchange Rates by Multifrequency Excitation 15N CEST: Application to Protein Phase Separation
T Yuwen, A Bah, JP Brady, F Ferrage, G Bouvignies, LE Kay
The Journal of Physical Chemistry B 122 (49), 11206-11217, 2018
242018
Domain cooperativity in multidomain proteins: what can we learn from molecular alignment in anisotropic media?
T Yuwen, CB Post, NR Skrynnikov
Journal of biomolecular NMR 51, 131-150, 2011
212011
PDTAC: targeted photodegradation of GPX4 triggers ferroptosis and potent antitumor immunity
S Liu, X Zhao, S Shui, B Wang, Y Cui, S Dong, T Yuwen, G Liu
Journal of Medicinal Chemistry 65 (18), 12176-12187, 2022
202022
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Artículos 1–20