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Alvin Joselin
Alvin Joselin
Dirección de correo verificada de ucalgary.ca
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ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
AP Joselin, SJ Hewitt, SM Callaghan, RH Kim, YH Chung, TW Mak, ...
Human molecular genetics 21 (22), 4888-4903, 2012
2402012
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
H Aleyasin, MWC Rousseaux, PC Marcogliese, SJ Hewitt, I Irrcher, ...
Proceedings of the National Academy of Sciences 107 (7), 3186-3191, 2010
1952010
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
NMC Connolly, P Theurey, V Adam-Vizi, NG Bazan, P Bernardi, ...
Cell Death & Differentiation 25 (3), 542-572, 2018
1472018
Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β
X Gao, AP Joselin, L Wang, A Kar, P Ray, A Bateman, AM Goate, JY Wu
Protein & cell 1, 552-562, 2010
1452010
Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis
AP Joselin, K Schulze-Osthoff, C Schwerk
Journal of Biological Chemistry 281 (18), 12475-12484, 2006
612006
BAG2 gene-mediated regulation of PINK1 protein is critical for mitochondrial translocation of PARKIN and neuronal survival
D Qu, A Hage, K Don-Carolis, E Huang, A Joselin, F Safarpour, ...
Journal of Biological Chemistry 290 (51), 30441-30452, 2015
592015
Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons
P Theurey, NMC Connolly, I Fortunati, E Basso, S Lauwen, C Ferrante, ...
Aging Cell 18 (3), e12924, 2019
542019
Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP+
W Boonying, A Joselin, E Huang, D Qu, F Safarpour, GO Iyirhiaro, ...
Journal of neurochemistry 150 (3), 312-329, 2019
412019
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
L Naia, CM Pinho, G Dentoni, J Liu, NS Leal, DMS Ferreira, B Schreiner, ...
BMC biology 19, 1-21, 2021
292021
The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors
T Huang, YR González, D Qu, E Huang, F Safarpour, E Wang, A Joselin, ...
Journal of Biological Chemistry 294 (21), 8617-8629, 2019
142019
Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition
DS Im, A Joselin, D Svoboda, T Takano, MWC Rousseaux, S Callaghan, ...
BMC biology 20 (1), 115, 2022
42022
PFTK1 kinase regulates axogenesis during development via RhoA activation
YR González, F Kamkar, P Jafar-Nejad, S Wang, D Qu, LS Alvarez, ...
BMC biology 21 (1), 240, 2023
22023
Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
JLA Parmasad, KM Ricke, B Nguyen, MG Stykel, B Buchner-Duby, ...
Cell Death & Disease 15 (4), 246, 2024
12024
Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
MWC Rousseaux, JL Parmasad, K Ricke, M Stykel, B Buchner-Duby, ...
2023
Screening, identification and pre-clinical validation of novel phagocytosis modulators using Parkinson's disease patients' macrophages and LRRK2 G2019S immune cells
R Ibrahim, D Qu, A Joselin, D Park
CLINICAL BIOCHEMISTRY 109, 122-122, 2022
2022
Genetic and pharmacological reduction of CDK14 mitigates α-synuclein pathology in human neurons and in rodent models of Parkinson’s disease
JLA Parmasad, KM Ricke, MG Stykel, B Buchner-Duby, B Nguyen, ...
bioRxiv, 2022.05. 02.490309, 2022
2022
PFTK1 kinase regulates axogenesis during development via RhoA activation
F Kamkar, P Jafar-nejad, S Wang, D Qu, D Hawari, M Sonnenfeld, ...
2022
RESEARCH ARTICLE Progranulin promotes neurite outgrowth and
X Gao, AP Joselin, L Wang, A Kar, P Ray, A Bateman, AM Goate, JY Wu
2010
The role of the apoptosis and splicing associated protein Acinus during apoptotic nuclear changes
AP Joselin
2006
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Artículos 1–19