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Gustavo Contreras
Gustavo Contreras
Research Professional, University of Chicago
Dirección de correo verificada de uchicago.edu
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A BK (Slo1) channel journey from molecule to physiology
GF Contreras, K Castillo, N Enrique, W Carrasquel-Ursulaez, JP Castillo, ...
Channels 7 (6), 442-458, 2013
1622013
Modulation of BK channel voltage gating by different auxiliary β subunits
GF Contreras, A Neely, O Alvarez, C Gonzalez, R Latorre
Proceedings of the National Academy of Sciences 109 (46), 18991-18996, 2012
1122012
Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1
MD Clark, GF Contreras, R Shen, E Perozo
Nature 583 (7814), 145-149, 2020
552020
The conformational cycle of prestin underlies outer-hair cell electromotility
N Bavi, MD Clark, GF Contreras, R Shen, BG Reddy, W Milewski, ...
Nature 600 (7889), 553-558, 2021
492021
Molecular mechanism underlying β1 regulation in voltage-and calcium-activated potassium (BK) channels
K Castillo, GF Contreras, A Pupo, YP Torres, A Neely, C González, ...
Proceedings of the National Academy of Sciences 112 (15), 4809-4814, 2015
372015
Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: New therapeutics opportunities as targets in human diseases
FJ Morera, J Saravia, JP Pontigo, L Vargas-Chacoff, GF Contreras, ...
Pharmacological Research 101, 56-64, 2015
192015
The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels
IE García, F Villanelo, GF Contreras, A Pupo, BI Pinto, JE Contreras, ...
Journal of General Physiology 150 (5), 697-711, 2018
182018
Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel
W Carrasquel-Ursulaez, GF Contreras, RV Sepúlveda, D Aguayo, ...
Journal of General Physiology 145 (1), 61-74, 2015
182015
Voltage sensor of ion channels and enzymes
C Gonzalez, GF Contreras, A Peyser, P Larsson, A Neely, R Latorre
Biophysical reviews 4, 1-15, 2012
182012
Slow Inactivation in Shaker K Channels Is Delayed by Intracellular Tetraethylammonium
V González-Pérez, A Neely, C Tapia, G González-Gutiérrez, G Contreras, ...
The Journal of general physiology 132 (6), 633-650, 2008
172008
Voltage-gated proton (Hv1) channels, a singular voltage sensing domain
K Castillo, A Pupo, D Baez-Nieto, GF Contreras, FJ Morera, A Neely, ...
FEBS letters 589 (22), 3471-3478, 2015
142015
Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes
G Gonzalez-Gutierrez, E Miranda-Laferte, G Contreras, A Neely, ...
Channels 4 (1), 42-50, 2010
102010
Keeping you healthy: BK channel activation by omega-3 fatty acids
R Latorre, G Contreras
Journal of General Physiology 142 (5), 487-491, 2013
72013
Cryo-EM structures of prestin and the molecular basis of outer hair cell electromotility
N Bavi, MD Clark, GF Contreras, R Shen, B Reddy, W Milewski, E Perozo
bioRxiv, 2021.08. 06.455374, 2021
42021
An optimized protocol for on-column nanodisc formation
MD Clark, GF Contreras, N Bavi, PR Haller, E Perozo
Biophysical Journal 121 (3), 464a-465a, 2022
22022
Structural Basis of Voltage-Dependent Gating in BK Channels and Its Coupling to the Calcium Sensor
GF Contreras, R Shen, R Latorre, E Perozo
bioRxiv, 2023.12. 29.573674, 2023
12023
Gating currents of monomeric Hv channel reveals a permeation pathway coupled to the voltage activation
D Baez-Nieto, E Otarola, G Contreras, P Larsson, R Latorre, C Gonzalez
Biophysical Journal 106 (2), 233a, 2014
12014
NS1619 activates the BK channel by stabilizing S6 helix and strengthens electromechanical coupling
N Gonzalez-Sanabria, GF Contreras, Y Duarte, D González, E Perozo, ...
Biophysical Journal 123 (3), 526a-527a, 2024
2024
BK channel voltage-gating mechanism probed by single-particle cryo-EM
GF Contreras, R Latorre, E Perozo
Biophysical Journal 123 (3), 314a-315a, 2024
2024
Prestin's structural cycle and the molecular basis of electromotility in outer hair cells
N Bavi, MD Clark, GF Contreras, R Shen, B Reddy, W Milewski, E Perozo
Biophysical Journal 121 (3), 18a, 2022
2022
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Artículos 1–20