Shuxing Zhang
Shuxing Zhang
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Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
NT Ihle, LA Byers, ES Kim, P Saintigny, JJ Lee, GR Blumenschein, A Tsao, ...
Journal of the National Cancer Institute 104 (3), 228-239, 2012
Polypharmacology: drug discovery for the future
AS Reddy, S Zhang
Expert review of clinical pharmacology 6 (1), 41-47, 2013
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
JP Robichaux, YY Elamin, Z Tan, BW Carter, S Zhang, S Liu, S Li, T Chen, ...
Nature medicine 24 (5), 638-646, 2018
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression
CH Chan, JK Morrow, CF Li, Y Gao, G Jin, A Moten, LJ Stagg, JE Ladbury, ...
Cell 154 (3), 556-568, 2013
First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics
B Wu, K Kulkarni, S Basu, S Zhang, M Hu
Journal of pharmaceutical sciences 100 (9), 3655-3681, 2011
A ROR1–HER3–lncRNA signalling axis modulates the Hippo–YAP pathway to regulate bone metastasis
C Li, S Wang, Z Xing, A Lin, K Liang, J Song, Q Hu, J Yao, Z Chen, ...
Nature cell biology 19 (2), 106-119, 2017
A novel automated lazy learning QSAR (ALL-QSAR) approach: method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models
S Zhang, A Golbraikh, S Oloff, H Kohn, A Tropsha
Journal of chemical information and modeling 46 (5), 1984-1995, 2006
Rho kinases play an obligatory role in vertebrate embryonic organogenesis
L Wei, W Roberts, L Wang, M Yamada, S Zhang, Z Zhao, SA Rivkees, ...
Oxford University Press for The Company of Biologists Limited 128 (15), 2953 …, 2001
Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors
JF Islas, Y Liu, KC Weng, MJ Robertson, S Zhang, A Prejusa, J Harger, ...
Proceedings of the National Academy of Sciences 109 (32), 13016-13021, 2012
Small molecule compounds targeting miRNAs for cancer therapy
PC Monroig, L Chen, S Zhang, GA Calin
Advanced drug delivery reviews 81, 104-116, 2015
Targeting microRNAs with small molecules: from dream to reality
S Zhang, L Chen, EJ Jung, GA Calin
Clinical Pharmacology & Therapeutics 87 (6), 754-758, 2010
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer
W Yao, JL Rose, W Wang, S Seth, H Jiang, A Taguchi, J Liu, L Yan, ...
Nature 568 (7752), 410-414, 2019
Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets
Z Niu, W Yu, SX Zhang, M Barron, NS Belaguli, MD Schneider, ...
Journal of Biological Chemistry 280 (37), 32531-32538, 2005
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
F Han, CF Li, Z Cai, X Zhang, G Jin, WN Zhang, C Xu, CY Wang, J Morrow, ...
Nature communications 9 (1), 4728, 2018
Serum response factor micromanaging cardiogenesis
Z Niu, A Li, SX Zhang, RJ Schwartz
Current opinion in cell biology 19 (6), 618-627, 2007
DOVIS: an implementation for high-throughput virtual screening using AutoDock
S Zhang, K Kumar, X Jiang, A Wallqvist, J Reifman
BMC bioinformatics 9, 1-4, 2008
Extracellular glutamate is increased in thalamus during thiamine deficiency‐induced lesions and is blocked by MK‐801
PJ Langlais, SX Zhang
Journal of neurochemistry 61 (6), 2175-2182, 1993
Development of Quantitative Structure− Binding Affinity Relationship Models Based on Novel Geometrical Chemical Descriptors of the Protein− Ligand Interfaces
S Zhang, A Golbraikh, A Tropsha
Journal of medicinal chemistry 49 (9), 2713-2724, 2006
Computational prediction of protein hot spot residues
J Kenneth Morrow, S Zhang
Current pharmaceutical design 18 (9), 1255-1265, 2012
From laptop to benchtop to bedside: structure-based drug design on protein targets
L Chen, J K Morrow, H T Tran, S S Phatak, L Du-Cuny, S Zhang
Current pharmaceutical design 18 (9), 1217-1239, 2012
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