Saraswati Sukumar
Saraswati Sukumar
Professor of Oncology
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Cited by
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ...
nature 464 (7291), 1071-1076, 2010
The genomic landscapes of human breast and colorectal cancers
LD Wood, DW Parsons, S Jones, J Lin, T Sjoblom, RJ Leary, D Shen, ...
Science 318 (5853), 1108-1113, 2007
Molecular definition of breast tumor heterogeneity
M Shipitsin, LL Campbell, P Argani, S Weremowicz, N Bloushtain-Qimron, ...
Cancer cell 11 (3), 259-273, 2007
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ...
Nature genetics 43 (7), 621-629, 2011
Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
H Zarbl, S Sukumar, AV Arthur, D Martin-Zanca, M Barbacid
Nature 315 (6018), 382-385, 1985
Analysis of human transcriptomes
VE Velculescu, SL Madden, L Zhang, AE Lash, J Yu, C Rago, A Lal, ...
Nature genetics 23 (4), 387-388, 1999
The Hox genes and their roles in oncogenesis
N Shah, S Sukumar
Nature Reviews Cancer 10 (5), 361-371, 2010
Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations
S Sukumar, V Notario, D Martin-Zanca, M Barbacid
Nature 306 (5944), 658-661, 1983
Compromised HOXA5 function can limit p53 expression in human breast tumours
V Raman, SA Martensen, D Reisman, E Evron, WF Odenwald, E Jaffee, ...
Nature 405 (6789), 974-978, 2000
Molecular links between obesity and breast cancer
AM Lorincz, S Sukumar
Endocrine-related cancer 13 (2), 279-292, 2006
High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer
AT Ferguson, E Evron, CB Umbricht, TK Pandita, TA Chan, H Hermeking, ...
Proceedings of the National Academy of Sciences 97 (11), 6049-6054, 2000
Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast
SL Kominsky, P Argani, D Korz, E Evron, V Raman, E Garrett, A Rein, ...
Oncogene 22 (13), 2021-2033, 2003
DNA methylation regulates MicroRNA expression
L Han, PDW Witmer, E Casey, D Valle, S Sukumar
Cancer biology & therapy 6 (8), 1290-1294, 2007
Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR
E Evron, WC Dooley, CB Umbricht, D Rosenthal, N Sacchi, E Gabrielson, ...
The Lancet 357 (9265), 1335-1336, 2001
HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
H Zhang, CCL Wong, H Wei, DM Gilkes, P Korangath, P Chaturvedi, ...
Oncogene 31 (14), 1757-1770, 2012
Hypermethylation of 14-3-3 σ (stratifin) is an early event in breast cancer
CB Umbricht, E Evron, E Gabrielson, A Ferguson, J Marks, S Sukumar
Oncogene 20 (26), 3348-3353, 2001
Activation of ras oncogenes preceding the onset of neoplasia
R Kumar, S Sukumar, M Barbacid
Science 248 (4959), 1101-1104, 1990
Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer
M Nacht, AT Ferguson, W Zhang, JM Petroziello, BP Cook, YH Gao, ...
Cancer Research 59 (21), 5464-5470, 1999
Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer
MJ Fackler, M McVeigh, J Mehrotra, MA Blum, J Lange, A Lapides, ...
Cancer research 64 (13), 4442-4452, 2004
Store-independent activation of Orai1 by SPCA2 in mammary tumors
M Feng, DM Grice, HM Faddy, N Nguyen, S Leitch, Y Wang, S Muend, ...
Cell 143 (1), 84-98, 2010
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