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Nicholas A. Clark
Nicholas A. Clark
Harvard Medical School
Dirección de correo verificada de hms.harvard.edu - Página principal
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The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
3902018
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ...
Nucleic acids research 46 (D1), D558-D566, 2018
1682018
GRcalculator: an online tool for calculating and mining dose–response data
NA Clark, M Hafner, M Kouril, EH Williams, JL Muhlich, M Pilarczyk, ...
BMC cancer 17, 1-11, 2017
812017
Cheminformatics tools for analyzing and designing optimized small-molecule collections and libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
642019
Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS
M Pilarczyk, M Kouril, B Shamsaei, J Vasiliauskas, W Niu, N Mahi, ...
BioRxiv, 826271, 2019
412019
Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy
JA Stefely, Y Zhang, EC Freiberger, NW Kwiecien, HE Thomas, AM Davis, ...
Autophagy 16 (12), 2219-2237, 2020
392020
Connecting omics signatures and revealing biological mechanisms with iLINCS
M Pilarczyk, M Fazel-Najafabadi, M Kouril, B Shamsaei, J Vasiliauskas, ...
Nature Communications 13 (1), 4678, 2022
352022
Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop
CE Mills, K Subramanian, M Hafner, M Niepel, L Gerosa, M Chung, ...
Nature Communications 13 (1), 6918, 2022
92022
Predicting mechanism of action of cellular perturbations with pathway activity signatures
Y Ren, S Sivaganesan, NA Clark, L Zhang, J Biesiada, W Niu, DR Plas, ...
Bioinformatics 36 (18), 4781-4788, 2020
82020
Multiplexed and reproducible high content screening of live and fixed cells using the Dye Drop method
CE Mills, K Subramanian, M Hafner, M Niepel, L Gerosa, M Chung, ...
bioRxiv, 2021.08. 27.457854, 2021
52021
CSIG-16. EXPLOITING A NEGATIVE FEEDBACK LOOP LINKING S6 KINASES AND AXL TO REDUCE PYRIMIDINE BIOSYNTHESIS IN PTEN-DEFICIENT GLIOBLASTOMA
C Behrmann, P Sarma, K Ennis, C Wetzel, N Clark, S Vallabhapurapu, ...
Neuro-Oncology 24 (Suppl 7), vii42, 2022
2022
Deep Dye Drop Protocol
C Victor, B Gaudio, M Chung, M Niepel, M Hafner, L Gerosa, C Yapp, ...
2022
Integrative signatures of signaling pathway response increase robustness and accuracy of pathway predictions
NA Clark, Y Ren, DR Plas, S Sivaganesan, M Medvedovic
bioRxiv, 2022.06. 03.494712, 2022
2022
Creating integrative signatures of signaling pathway activity from diverse cell lines
NA Clark
University of Cincinnati, 2021
2021
HIGHLY ACTIVE ANTIRETROVIRAL THERAPY: MODELING AND OPTIMIZING HIV TREATMENT
N CLARK, H JOSHI
Neural, Parallel, and Scientific Computations 22, 289-302, 2014
2014
Supplemental Results
M Pilarczyk, M Fazel-Najafabadi, M Kouril, B Shamsaei, J Vasiliauskas, ...
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