Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation JH Park, KH Lee, TY Kim, SY Lee Proceedings of the national academy of sciences 104 (19), 7797-7802, 2007 | 653 | 2007 |
Systems metabolic engineering of Escherichia coli for l‐threonine production KH Lee, JH Park, TY Kim, HU Kim, SY Lee Molecular systems biology 3 (1), 149, 2007 | 543 | 2007 |
Systems biotechnology for strain improvement SY Lee, DY Lee, TY Kim TRENDS in Biotechnology 23 (7), 349-358, 2005 | 428 | 2005 |
Metabolic Engineering of Escherichia coli for Enhanced Production of Succinic Acid, Based on Genome Comparison and In Silico Gene Knockout Simulation SJ Lee, DY Lee, TY Kim, BH Kim, J Lee, SY Lee Applied and environmental microbiology 71 (12), 7880-7887, 2005 | 363 | 2005 |
Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers YK Jung, TY Kim, SJ Park, SY Lee Biotechnology and bioengineering 105 (1), 161-171, 2010 | 321 | 2010 |
In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production HS Choi, SY Lee, TY Kim, HM Woo Applied and environmental microbiology 76 (10), 3097-3105, 2010 | 303 | 2010 |
Metabolic engineering of Corynebacterium glutamicum for L-arginine production SH Park, HU Kim, TY Kim, JS Park, SS Kim, SY Lee Nature communications 5 (1), 4618, 2014 | 259 | 2014 |
Recent advances in reconstruction and applications of genome-scale metabolic models TY Kim, SB Sohn, YB Kim, WJ Kim, SY Lee Current opinion in biotechnology 23 (4), 617-623, 2012 | 248 | 2012 |
Application of systems biology for bioprocess development JH Park, SY Lee, TY Kim, HU Kim Trends in biotechnology 26 (8), 404-412, 2008 | 223 | 2008 |
Systems metabolic engineering for chemicals and materials JW Lee, TY Kim, YS Jang, S Choi, SY Lee Trends in biotechnology 29 (8), 370-378, 2011 | 206 | 2011 |
Integrative genome‐scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery HU Kim, SY Kim, H Jeong, TY Kim, JJ Kim, HE Choy, KY Yi, JH Rhee, ... Molecular systems biology 7 (1), 460, 2011 | 200 | 2011 |
Metabolic flux analysis and metabolic engineering of microorganisms HU Kim, TY Kim, SY Lee Molecular BioSystems 4 (2), 113-120, 2008 | 183 | 2008 |
Metabolic engineering of microorganisms: general strategies and drug production SY Lee, HU Kim, JH Park, JM Park, TY Kim Drug Discovery Today 14 (1-2), 78-88, 2009 | 169 | 2009 |
Constraints-based genome-scale metabolic simulation for systems metabolic engineering JM Park, TY Kim, SY Lee Biotechnology advances 27 (6), 979-988, 2009 | 159 | 2009 |
Metabolite essentiality elucidates robustness of Escherichia coli metabolism PJ Kim, DY Lee, TY Kim, KH Lee, H Jeong, SY Lee, S Park Proceedings of the National Academy of Sciences 104 (34), 13638-13642, 2007 | 156 | 2007 |
Systems biology as a foundation for genome-scale synthetic biology CL Barrett, TY Kim, HU Kim, BØ Palsson, SY Lee Current opinion in biotechnology 17 (5), 488-492, 2006 | 156 | 2006 |
Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production J Nocon, MG Steiger, M Pfeffer, SB Sohn, TY Kim, M Maurer, H Rußmayer, ... Metabolic Engineering 24, 129-138, 2014 | 152 | 2014 |
Genome‐scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production SB Sohn, AB Graf, TY Kim, B Gasser, M Maurer, P Ferrer, D Mattanovich, ... Biotechnology journal 5 (7), 705-715, 2010 | 148 | 2010 |
Metabolic engineering of Escherichia coli for the production of malic acid SY Moon, SH Hong, TY Kim, SY Lee Biochemical Engineering Journal 40 (2), 312-320, 2008 | 146 | 2008 |
Recent advances in production of recombinant spider silk proteins H Chung, TY Kim, SY Lee Current opinion in biotechnology 23 (6), 957-964, 2012 | 145 | 2012 |