Seguir
Edgar E Boczek
Edgar E Boczek
Dewpoint Therapeutics
Dirección de correo verificada de dewpointx.com
Título
Citado por
Citado por
Año
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function
D Mateju, TM Franzmann, A Patel, A Kopach, EE Boczek, S Maharana, ...
The EMBO journal 36 (12), 1669-1687, 2017
4242017
Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90
EE Boczek, LG Reefschläger, M Dehling, TJ Struller, E Häusler, A Seidl, ...
Proceedings of the National Academy of Sciences 112 (25), E3189-E3198, 2015
972015
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
872019
Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting
B Dreier, G Mikheeva, N Belousova, P Parizek, E Boczek, I Jelesarov, ...
Journal of molecular biology 405 (2), 410-426, 2011
612011
Features of the chaperone cellular network revealed through systematic interaction mapping
K Rizzolo, J Huen, A Kumar, S Phanse, J Vlasblom, Y Kakihara, ...
Cell reports 20 (11), 2735-2748, 2017
602017
HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain
EE Boczek, J Fürsch, ML Niedermeier, L Jawerth, M Jahnel, M Ruer-Gruß, ...
Elife 10, e69377, 2021
452021
Hsp90 dependence of a kinase is determined by its conformational landscape
Q Luo, EE Boczek, Q Wang, J Buchner, VRI Kaila
Scientific reports 7 (1), 43996, 2017
292017
Autophosphorylation activates c-Src kinase through global structural rearrangements
EE Boczek, Q Luo, M Dehling, M Röpke, SL Mader, A Seidl, VRI Kaila, ...
Journal of Biological Chemistry 294 (35), 13186-13197, 2019
202019
Phase changes in neurotransmission
EE Boczek, S Alberti
Science 361 (6402), 548-549, 2018
92018
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv. 2019; 721001
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
Google Scholar][CrossRef][Green Version], 0
8
One domain fits all: Using disordered regions to sequester misfolded proteins
EE Boczek, S Alberti
The Journal of cell biology 217 (4), 1173, 2018
72018
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv: 721001
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
42019
Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process
D Choudhary, L Mediani, MJ Avellaneda, S Bjarnason, S Alberti, ...
Journal of the American Chemical Society 145 (28), 15188-15196, 2023
22023
The first Autumn School on Proteostasis: from molecular mechanisms to organismal consequences
E Boczek, G Gaglia, M Olshina, S Sarraf
Cell Stress and Chaperones 24 (3), 481-492, 2019
22019
Methods of characterizing condensate-associated characteristics of compounds and uses thereof
BA Beutel, PJ Dandliker, SP Hale, MA Murcko, EE Boczek, M Mittasch, ...
US Patent 11,493,519, 2022
12022
Methods of identifying interactions of a compound and a condensate, or a component thereof, and uses thereof
DM Mitrea, M Mittasch, PJ Dandliker, BA Beutel, EE Boczek
US Patent App. 18/020,897, 2023
2023
Methods of characterizing condensate-associated characteristics of compounds and uses thereof
BA Beutel, PJ Dandliker, SP Hale, MA Murcko, EE Boczek, M Mittasch, ...
US Patent App. 17/960,702, 2023
2023
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models
H Uechi, S Sridharan, J Nijssen, J Bilstein, JM Iglesias-Artola, S Kishigami, ...
bioRxiv, 721001, 2019
2019
Three complementary mechanisms of quality control ensure RNP granule functionality and dynamics.
D Mateju, E Boczek, J Wang, A Kopach, S Maharana, A Patel, HO Lee, ...
MOLECULAR BIOLOGY OF THE CELL 27, 2016
2016
The maturation of Src kinase by the molecular chaperone Hsp90 and its kinase specific cochaperone Cdc37
E Boczek
Technische Universität München, 2015
2015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20