Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh*, B Izar*, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3096 | 2016 |
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 819 | 2016 |
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 770 | 2018 |
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma D Liu, B Schilling, D Liu, A Sucker, E Livingstone, L Jerby-Arnon, ... Nature medicine 25 (12), 1916-1927, 2019 | 417 | 2019 |
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger Elife 7, 2018 | 372 | 2018 |
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ... Nature 595 (7865), 107-113, 2021 | 371 | 2021 |
Ex vivo profiling of PD-1 blockade using organotypic tumor SpheroidsEx vivo profiling of immune checkpoint blockade RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ... Cancer discovery 8 (2), 196-215, 2018 | 341 | 2018 |
A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 268 | 2021 |
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature medicine 26 (5), 792-802, 2020 | 268 | 2020 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 253 | 2020 |
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ... Molecular systems biology 13 (1), 905, 2017 | 210 | 2017 |
A single-cell landscape of high-grade serous ovarian cancer B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ... Nature medicine 26 (8), 1271-1279, 2020 | 202 | 2020 |
Superior skin cancer classification by the combination of human and artificial intelligence A Hekler, JS Utikal, AH Enk, A Hauschild, M Weichenthal, RC Maron, ... European Journal of Cancer 120, 114-121, 2019 | 201 | 2019 |
IFNγ-dependent tissue-immune homeostasis is co-opted in the tumor microenvironment CJ Nirschl, M Suárez-Fariñas, B Izar, S Prakadan, R Dannenfelser, ... Cell 170 (1), 127-141. e15, 2017 | 136 | 2017 |
Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation A Rotem, A Janzer, B Izar, Z Ji, JG Doench, LA Garraway, K Struhl Proceedings of the National Academy of Sciences 112 (18), 5708-5713, 2015 | 116 | 2015 |
Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 110 | 2021 |
The Impact of EGFR Mutation Status on Outcomes in Patients With Resected Stage I Non-Small Cell Lung Cancers B Izar, L Sequist, M Lee, A Muzikansky, R Heist, J Iafrate, ... The Annals of thoracic surgery, 2013 | 104 | 2013 |
Harrisons Manual of Oncology 2/E B Chabner, T Lynch, D Longo McGraw-Hill Education, 2013 | 96 | 2013 |
Universal Stress Proteins Are Important for Oxidative and Acid Stress Resistance and Growth of Listeria monocytogenes EGD-e In Vitro and In Vivo C Seifart Gomes, B Izar, F Pazan, W Mohamed, MA Mraheil, K Mukherjee, ... PLoS One 6 (9), e24965, 2011 | 91 | 2011 |
Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes T Hain, R Ghai, A Billion, CT Kuenne, C Steinweg, B Izar, W Mohamed, ... BMC genomics 13, 1-17, 2012 | 90 | 2012 |