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Jake A. Kushner M.D.
Jake A. Kushner M.D.
President and CEO, Invectys, Inc
Dirección de correo verificada de mcnair.com - Página principal
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Cloning and expression of human and rat Dt dopamine receptors
QY Zhou, DK Grandy, L Thambi, JA Kushner, HHMV Tol, R Cone, ...
Nature 347 (6288), 76-80, 1990
8061990
Growth and regeneration of adult β cells does not involve specialized progenitors
M Teta, MM Rankin, SY Long, GM Stein, JA Kushner
Developmental cell 12 (5), 817-826, 2007
6812007
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
M Schubert, DP Brazil, DJ Burks, JA Kushner, J Ye, CL Flint, ...
Journal of Neuroscience 23 (18), 7084-7092, 2003
6162003
Very slow turnover of β-cells in aged adult mice
M Teta, SY Long, LM Wartschow, MM Rankin, JA Kushner
Diabetes 54 (9), 2557-2567, 2005
6042005
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
MJ Kiel, S He, R Ashkenazi, SN Gentry, M Teta, JA Kushner, TL Jackson, ...
Nature 449 (7159), 238-242, 2007
5212007
Cyclins D2 and D1 are essential for postnatal pancreatic β-cell growth
JA Kushner, MA Ciemerych, E Sicinska, LM Wartschow, M Teta, SY Long, ...
Molecular and cellular biology 25 (9), 3752-3762, 2005
4312005
Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals
DB Pawlak, JA Kushner, DS Ludwig
The Lancet 364 (9436), 778-785, 2004
4202004
Effects of sotagliflozin added to insulin in patients with type 1 diabetes
SK Garg, RR Henry, P Banks, JB Buse, MJ Davies, GR Fulcher, P Pozzilli, ...
New England Journal of Medicine 377 (24), 2337-2348, 2017
3952017
Adaptive β-cell proliferation is severely restricted with advanced age
MM Rankin, JA Kushner
Diabetes 58 (6), 1365-1372, 2009
3802009
Dysregulation of insulin receptor substrate 2 in β cells and brain causes obesity and diabetes
X Lin, A Taguchi, S Park, JA Kushner, F Li, Y Li, MF White
The Journal of clinical investigation 114 (7), 908-916, 2004
3752004
International consensus on risk management of diabetic ketoacidosis in patients with type 1 diabetes treated with sodium–glucose cotransporter (SGLT) inhibitors
T Danne, S Garg, AL Peters, JB Buse, C Mathieu, JH Pettus, ...
Diabetes care 42 (6), 1147-1154, 2019
2962019
Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined by in Vivo Thymidine Analog Incorporation and Radiocarbon Dating
S Perl, JA Kushner, BA Buchholz, AK Meeker, GM Stein, M Hsieh, M Kirby, ...
The Journal of Clinical Endocrinology & Metabolism 95 (10), E234-E239, 2010
2952010
Pdx1 restores β cell function in Irs2 knockout mice
JA Kushner, J Ye, M Schubert, DJ Burks, MA Dow, CL Flint, S Dutta, ...
The Journal of clinical investigation 109 (9), 1193-1201, 2002
2292002
miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner
NS Chitnis, D Pytel, E Bobrovnikova-Marjon, D Pant, H Zheng, NL Maas, ...
Molecular cell 48 (3), 353-364, 2012
2272012
β-cell mass and type 1 diabetes: going, going, gone?
E Akirav, JA Kushner, KC Herold
Diabetes 57 (11), 2883-2888, 2008
2132008
Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of β-cells
NA Sherry, W Chen, JA Kushner, M Glandt, Q Tang, S Tsai, P Santamaria, ...
Endocrinology 148 (11), 5136-5144, 2007
2092007
Sotagliflozin in combination with optimized insulin therapy in adults with type 1 diabetes: the North American inTandem1 study
JB Buse, SK Garg, J Rosenstock, TS Bailey, P Banks, BW Bode, T Danne, ...
Diabetes care 41 (9), 1970-1980, 2018
2062018
The diabetes susceptibility gene Clec16a regulates mitophagy
SA Soleimanpour, A Gupta, M Bakay, AM Ferrari, DN Groff, J Fadista, ...
Cell 157 (7), 1577-1590, 2014
1982014
The role of aging upon β cell turnover
JA Kushner
The Journal of clinical investigation 123 (3), 990-995, 2013
1972013
Effects of autoimmunity and immune therapy on β-cell turnover in type 1 diabetes
NA Sherry, JA Kushner, M Glandt, T Kitamura, AMB Brillantes, KC Herold
Diabetes 55 (12), 3238-3245, 2006
1892006
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