| Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate C Schmitz-Peiffer, DL Craig, TJ Biden Journal of Biological Chemistry 274 (34), 24202-24210, 1999 | 739 | 1999 |
| Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells. LA Selbie, C Schmitz-Peiffer, Y Sheng, TJ Biden Journal of Biological Chemistry 268 (32), 24296-24302, 1993 | 452 | 1993 |
| Alterations in the expression and cellular localization of protein kinase C isozymes ε and θ are associated with insulin resistance in skeletal muscle of the high-fat–fed rat C Schmitz-Peiffer, CL Browne, ND Oakes, A Watkinson, DJ Chisholm, ... Diabetes 46 (2), 169-178, 1997 | 428 | 1997 |
| Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply C Schmitz-Peiffer Cellular signalling 12 (9-10), 583-594, 2000 | 371 | 2000 |
| A role for protein phosphatase 2A–like activity, but not atypical protein kinase Cζ, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate R Cazzolli, L Carpenter, TJ Biden, C Schmitz-Peiffer Diabetes 50 (10), 2210-2218, 2001 | 191 | 2001 |
| Protein kinase C function in muscle, liver, and β-cells and its therapeutic implications for type 2 diabetes C Schmitz-Peiffer, TJ Biden Diabetes 57 (7), 1774, 2008 | 188 | 2008 |
| Protein kinase C and lipid‐induced insulin resistance in skeletal muscle C SCHMITZ‐PEIFFER Annals of the New York Academy of Sciences 967 (1), 146-157, 2002 | 179 | 2002 |
| Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat DR Laybutt, C Schmitz-Peiffer, AK Saha, NB Ruderman, TJ Biden, ... American Journal of Physiology-Endocrinology and Metabolism 277 (6), E1070-E1076, 1999 | 172 | 1999 |
| Inhibition of PKCɛ improves glucose-stimulated insulin secretion and reduces insulin clearance C Schmitz-Peiffer, DR Laybutt, JG Burchfield, E Gurisik, S Narasimhan, ... Cell metabolism 6 (4), 320-328, 2007 | 129 | 2007 |
| A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism N Turner, XY Lim, HD Toop, B Osborne, AE Brandon, EN Taylor, ... Nature communications 9 (1), 3165, 2018 | 116 | 2018 |
| Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2 MS Rolph, TR Young, BOV Shum, CZ Gorgun, C Schmitz-Peiffer, ... The Journal of Immunology 177 (11), 7794-7801, 2006 | 107 | 2006 |
| Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C θ JG Burchfield, AJ Lennard, S Narasimhan, WE Hughes, VC Wasinger, ... Journal of Biological Chemistry 279 (18), 18623-18632, 2004 | 107 | 2004 |
| Saturated-and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors G Frangioudakis, J Garrard, K Raddatz, JL Nadler, TW Mitchell, ... Endocrinology 151 (9), 4187-4196, 2010 | 96 | 2010 |
| IRS‐1 regulation in health and disease C Schmitz‐Peiffer, J Whitehead IUBMB life 55 (7), 367-374, 2003 | 93 | 2003 |
| Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653 C Schmitz-Peiffer, ND Oakes, CL Browne, EW Kraegen, TJ Biden American Journal of Physiology-Endocrinology and Metabolism 273 (5), E915-E921, 1997 | 87 | 1997 |
| Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species MK Montgomery, SHJ Brown, XY Lim, CE Fiveash, B Osborne, NL Bentley, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 81 | 2016 |
| Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ G Frangioudakis, JG Burchfield, S Narasimhan, GJ Cooney, M Leitges, ... Diabetologia 52, 2616-2620, 2009 | 77 | 2009 |
| Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice K Raddatz, N Turner, G Frangioudakis, BM Liao, DJ Pedersen, J Cantley, ... Diabetologia 54, 1447-1456, 2011 | 75 | 2011 |
| Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors X Luo, LJ Hutley, JA Webster, YH Kim, DF Liu, FS Newell, CH Widberg, ... Diabetes 61 (1), 124-136, 2012 | 74 | 2012 |
| Targeting ceramide synthesis to reverse insulin resistance C Schmitz-Peiffer Diabetes 59 (10), 2351, 2010 | 73 | 2010 |
