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Eric Bouffet
Eric Bouffet
Haematology/Oncology - Child Health Evaluative Sciences
Dirección de correo verificada de sickkids.ca
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Medulloblastoma comprises four distinct molecular variants
PA Northcott, A Korshunov, H Witt, T Hielscher, CG Eberhart, S Mack, ...
Journal of clinical oncology 29 (11), 1408, 2011
15082011
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer cell 31 (6), 737-754. e6, 2017
10332017
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124, 439-447, 2012
9552012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9542012
Novel mutations target distinct subgroups of medulloblastoma
G Robinson, M Parker, TA Kranenburg, C Lu, X Chen, L Ding, TN Phoenix, ...
Nature 488 (7409), 43-48, 2012
9082012
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ...
Journal of clinical oncology 34 (19), 2206-2211, 2016
8172016
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
6832017
Diffuse brainstem glioma in children: critical review of clinical trials
D Hargrave, U Bartels, E Bouffet
The lancet oncology 7 (3), 241-248, 2006
6802006
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6292014
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
6182014
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus
V Ramaswamy, M Remke, E Bouffet, S Bailey, SC Clifford, F Doz, M Kool, ...
Acta neuropathologica 131, 821-831, 2016
5992016
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ...
Journal of Clinical Oncology 31 (23), 2927, 2013
5032013
Change in neurocognitive functioning after treatment with cranial radiation in childhood
BJ Spiegler, E Bouffet, ML Greenberg, JT Rutka, DJ Mabbott
Journal of Clinical Oncology 22 (4), 706-713, 2004
4972004
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529-533, 2012
4802012
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ...
Acta neuropathologica 123, 615-626, 2012
4172012
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ...
The lancet oncology 14 (12), 1200-1207, 2013
3902013
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ...
Nature genetics 47 (3), 257-262, 2015
3642015
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of clinical oncology 32 (9), 886, 2014
3562014
Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential …
M Zarghooni, U Bartels, E Lee, P Buczkowicz, A Morrison, A Huang, ...
J clin oncol 28 (8), 1337-1344, 2010
3532010
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
EM Thompson, T Hielscher, E Bouffet, M Remke, B Luu, S Gururangan, ...
The lancet oncology 17 (4), 484-495, 2016
3482016
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Artículos 1–20