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Xiaobo Wang
Xiaobo Wang
Assistant Professor, Molecular Medicine, Columbia University
Dirección de correo verificada de columbia.edu
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Hepatocyte TAZ/WWTR1 promotes inflammation and fibrosis in nonalcoholic steatohepatitis
X Wang, ZE Zheng, JM Caviglia, KE Corey, TM Herfel, B Cai, R Masia, ...
Cell metabolism 24 (6), 848-862, 2016
3312016
Macrophage metabolism of apoptotic cell-derived arginine promotes continual efferocytosis and resolution of injury
A Yurdagul, M Subramanian, X Wang, SB Crown, OR Ilkayeva, L Darville, ...
Cell metabolism 31 (3), 518-533. e10, 2020
2692020
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
C Zhu, KJ Kim, X Wang, A Bartolome, M Salomao, P Dongiovanni, ...
Science translational medicine 10 (468), eaat0344, 2018
1812018
Macrophage MerTK promotes liver fibrosis in nonalcoholic steatohepatitis
B Cai, P Dongiovanni, KE Corey, X Wang, IO Shmarakov, Z Zheng, ...
Cell metabolism 31 (2), 406-421. e7, 2020
1802020
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice
W Tao, A Yurdagul Jr, N Kong, W Li, X Wang, AC Doran, C Feng, J Wang, ...
Science Translational Medicine 12 (553), eaay1063, 2020
1442020
Cholesterol stabilizes TAZ in hepatocytes to promote experimental non-alcoholic steatohepatitis
X Wang, B Cai, X Yang, OO Sonubi, ZE Zheng, R Ramakrishnan, H Shi, ...
Cell metabolism 31 (5), 969-986. e7, 2020
1282020
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandra, ...
Nature 610 (7931), 356-365, 2022
1192022
Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development
Y Wang, G Hu, F Liu, X Wang, M Wu, JJ Schwarz, J Zhou
Circulation research 114 (6), 957-965, 2014
1182014
Efferocytosis induces macrophage proliferation to help resolve tissue injury
BD Gerlach, PB Ampomah, A Yurdagul, C Liu, MC Lauring, X Wang, ...
Cell metabolism 33 (12), 2445-2463. e8, 2021
1092021
The induction of yes-associated protein expression after arterial injury is crucial for smooth muscle phenotypic modulation and neointima formation
X Wang, G Hu, X Gao, Y Wang, W Zhang, EY Harmon, X Zhi, Z Xu, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (11), 2662-2669, 2012
1062012
Repression of versican expression by microRNA-143
X Wang, G Hu, J Zhou
Journal of Biological Chemistry 285 (30), 23241-23250, 2010
1062010
Identification of microRNAs from different tissues of chicken embryo and adult chicken
H Xu, X Wang, Z Du, N Li
Febs Letters 580 (15), 3610-3616, 2006
812006
SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation
Z Xu, G Ji, J Shen, X Wang, J Zhou, L Li
Biochemical and biophysical research communications 422 (2), 285-290, 2012
642012
Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution
PB Ampomah, B Cai, SR Sukka, BD Gerlach, A Yurdagul Jr, X Wang, ...
Nature metabolism 4 (4), 444-457, 2022
632022
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis
J Yu, C Zhu, X Wang, KJ Kim, A Bartolome, P Dongiovanni, KP Yates, ...
Science translational medicine 13 (599), eabe1692, 2021
622021
Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin protein
X Wang, G Hu, C Betts, EY Harmon, RS Keller, L Van De Water, J Zhou
Journal of Biological Chemistry 286 (48), 41589-41599, 2011
622011
C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions
TI Zhou AX, Wang X, Lin CS, Han J, Yong J, Nadolski MJ, Borén J, Kaufman RJ
Circ Res 116 (11), 1736-43, 2015
592015
The Transcription Factor TEAD1 Represses Smooth Muscle-specific Gene Expression by Abolishing Myocardin Function*♦
F Liu, X Wang, G Hu, Y Wang, J Zhou
Journal of Biological Chemistry 289 (6), 3308-3316, 2014
552014
shRNA transcribed by RNA Pol II promoter induce RNA interference in mammalian cell
J Yuan, X Wang, Y Zhang, X Hu, X Deng, J Fei, N Li
Molecular biology reports 33, 43-49, 2006
452006
Modulation of myocardin function by the ubiquitin E3 ligase UBR5
G Hu, X Wang, DN Saunders, M Henderson, AJ Russell, BP Herring, ...
Journal of biological chemistry 285 (16), 11800-11809, 2010
442010
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