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Kenneth Gorelick
Kenneth Gorelick
Zymo Consulting Group LLC
Dirección de correo verificada de zymocon.com - Página principal
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A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis
RL Greenman, RMH Schein, MA Martin, RP Wenzel, NR Maclntyre, ...
Jama 266 (8), 1097-1102, 1991
9521991
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis …
JL Vincent, MK Ramesh, D Ernest, SP LaRosa, J Pachl, N Aikawa, ...
Critical care medicine 41 (9), 2069-2079, 2013
3342013
Effect of a recombinant human soluble thrombomodulin on mortality in patients with sepsis-associated coagulopathy: the SCARLET randomized clinical trial
JL Vincent, B Francois, I Zabolotskikh, MK Daga, JB Lascarrou, MY Kirov, ...
Jama 321 (20), 1993-2002, 2019
2722019
Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial
S Vermeire, WJ Sandborn, S Danese, X Hébuterne, BA Salzberg, ...
The Lancet 390 (10090), 135-144, 2017
1892017
Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: A double‐blind, randomized, placebo‐controlled trial
MA Petri, RG Lahita, RF Van Vollenhoven, JT Merrill, M Schiff, EM Ginzler, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2002
1892002
Results of a second double-blind, randomized, controlled trial of antiendotoxin antibody E5 in gram-negative sepsis
R Wenzel, R Bone, A Fein, R Quenzer, J Schentag, KJ Gorelick, N Wedel, ...
Program and abstracts of the 31st Interscience Conference on Antimicrobial …, 1991
1131991
Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn’s disease: report of the OPERA study
WJ Sandborn, SD Lee, D Tarabar, E Louis, M Klopocka, J Klaus, ...
Gut 67 (10), 1824-1835, 2018
1102018
Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complex
JO Kahn, KJ Gorelick, G Gatti, CJ Arri, JD Lifson, JG Gambertoglio, ...
Antimicrobial agents and chemotherapy 38 (2), 260-267, 1994
871994
The HA-1A monoclonal antibody for gram-negative sepsis
GA Schmidt
The New England journal of medicine 325 (4), 279-283, 1991
611991
Observations using antiendotoxin antibody (E5) as adjuvant therapy in humans with suspected, serious, gram-negative sepsis
RN GREENBERG, KM WILSON, AY KUNZ, NI WEDEL, KJ GORELICK
Critical care medicine 20 (6), 730-735, 1992
531992
Production and clinical development of a Hansenula polymorpha-derived PEGylated hirudin
GC Avgerinos, BG Turner, KJ Gorelick, A Papendieck, U Weydemann, ...
Seminars in thrombosis and hemostasis 27 (04), 357-372, 2001
472001
Results of a phase 2 trial of an oral CXCR4 antagonist, mavorixafor, for treatment of WHIM syndrome
DC Dale, F Firkin, AA Bolyard, M Kelley, V Makaryan, KJ Gorelick, ...
Blood, The Journal of the American Society of Hematology 136 (26), 2994-3003, 2020
462020
Results of the GL701 (DHEA) multicenter steroid-sparing SLE study.
M Petri, R Lahita, J McGuire, R vanVollenhoven, V Strand, A Kunz, ...
Arthritis and Rheumatism 40 (9), 1769-1769, 1997
311997
Randomized placebo-controlled study of E5 monoclonal antiendotoxin antibody
K Gorelick, PJ Scannon, J Hannigan, N Wedel, SK Ackerman
Therapeutic monoclonal antibodies, 253-261, 1990
301990
Long-term safety and efficacy of the anti-MAdCAM-1 monoclonal antibody ontamalimab [SHP647] for the treatment of ulcerative colitis: the open-label study TURANDOT II
W Reinisch, WJ Sandborn, S Danese, X Hébuterne, M Kłopocka, ...
Journal of Crohn's and Colitis 15 (6), 938-949, 2021
292021
Effect of PF-00547659 on central nervous system immune surveillance and circulating β7+ T cells in Crohn’s disease: report of the TOSCA study
G D’Haens, S Vermeire, H Vogelsang, M Allez, P Desreumaux, ...
Journal of Crohn's and Colitis 12 (2), 188-196, 2018
282018
Efficacy results of a randomized multicenter trial of E5 antiendotoxin monoclonal antibody in patients with suspected gram-negative sepsis
K Gorelick, R Jacobs, H Chmel, G Trenholme, R Greenman
Proceedings of the 29th International Conference on Antimicrobial Agents and …, 1989
261989
TURANDOT: a randomized, multicenter double-blind, placebo-controlled study of the safety and efficacy of Anti-MAdCAM Antibody PF-00547659 (PF) in patients with moderate to …
S Vermeire, W Sandborn, S Danese, X Hebuterne, B Salzberg, ...
Journal Of Crohns & Colitis 9, S13-S14, 2015
252015
A randomized, multicenter double-blind, placebo-controlled study of the safety and efficacy of anti-MAdCAM antibody PF-00547659 (PF) in patients with moderate to severe …
W Reinisch, W Sandborn, S Danese, F Cataldi, X Hebuterne, B Salzberg, ...
Gastroenterology 148 (4), S1193-S1193, 2015
222015
825 Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease: Results of the OPERA study
W Sandborn, SD Lee, D Tarabar, E Louis, M Klopocka, J Klaus, ...
Gastroenterology 148 (4), S-162, 2015
212015
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