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Alejandra Alvarez
Alejandra Alvarez
Verified email at bio.puc.cl
Title
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Cited by
Year
Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme
NC Inestrosa, A Alvarez, CA Perez, RD Moreno, M Vicente, C Linker, ...
Neuron 16 (4), 881-891, 1996
12821996
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
GV De Ferrari, MA Chacon, MI Barria, JL Garrido, JA Godoy, G Olivares, ...
Molecular psychiatry 8 (2), 195-208, 2003
4482003
Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils
A Alvarez, R Alarcon, C Opazo, EO Campos, FJ Munoz, FH Calderon, ...
Journal of Neuroscience 18 (9), 3213-3223, 1998
4231998
Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils
A Alvarez, C Opazo, R Alarcón, J Garrido, NC Inestrosa
Journal of molecular biology 272 (3), 348-361, 1997
3561997
Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death
A Alvarez, R Toro, A Cáceres, RB Maccioni
FEBS letters 459 (3), 421-426, 1999
3211999
Amyloid–cholinesterase interactions: implications for Alzheimer’s disease
NC Inestrosa, MC Dinamarca, A Alvarez
The FEBS journal 275 (4), 625-632, 2008
3142008
Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons
AR Alvarez, JA Godoy, K Mullendorff, GH Olivares, M Bronfman, ...
Experimental cell research 297 (1), 186-196, 2004
3012004
Protein kinase C inhibits amyloid β‐peptide neurotoxicity by acting on members of the Wnt pathway
JL Garrido, J Godoy, A Alvarez, M Bronfman, NC Inestrosa
The FASEB journal 16 (14), 1982-1984, 2002
2162002
A cdk5–p35 stable complex is involved in the β-amyloid-induced deregulation of cdk5 activity in hippocampal neurons
A Alvarez, JP Munoz, RB Maccioni
Experimental cell research 264 (2), 266-274, 2001
1762001
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits
GI Cancino, EM Toledo, NR Leal, DE Hernandez, LF Yévenes, ...
Brain 131 (9), 2425-2442, 2008
1712008
Activation of the neuronal c-Abl tyrosine kinase by amyloid-β-peptide and reactive oxygen species
AR Alvarez, PC Sandoval, NR Leal, PU Castro, KS Kosik
Neurobiology of disease 17 (2), 326-336, 2004
1632004
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann‐Pick type C disease
AR Alvarez, A Klein, J Castro, GI Cancino, J Amigo, M Mosqueira, ...
The FASEB Journal 22 (10), 3617-3627, 2008
1592008
c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice
GI Cancino, KP de Arce, PU Castro, EM Toledo, R von Bernhardi, ...
Neurobiology of aging 32 (7), 1249-1261, 2011
1292011
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
L Varela-Nallar, CP Grabowski, IE Alfaro, AR Alvarez, NC Inestrosa
Neural development 4, 1-15, 2009
1252009
Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease
MC Vázquez, E Balboa, AR Alvarez, S Zanlungo
Oxidative medicine and cellular longevity 2012, 2012
1242012
A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme
AE Reyes, DR Perez, A Alvarez, J Garrido, MK Gentry, BP Doctor, ...
Biochemical and biophysical research communications 232 (3), 652-655, 1997
1221997
Wnt signaling involvement in β-amyloid-dependent neurodegeneration
NC Inestrosa, GV De Ferrari, JL Garrido, A Alvarez, GH Olivares, MI Barrıa, ...
Neurochemistry international 41 (5), 341-344, 2002
1152002
Anti–ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice
M Bravo‐Zehnder, EM Toledo, F Segovia‐Miranda, FG Serrano, ...
Arthritis & rheumatology 67 (1), 204-214, 2015
1142015
Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer's filaments.
NC Inestrosa, A Alvarez, F Calderon
Molecular psychiatry 1 (5), 359-361, 1996
1081996
EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers
L M. Vargas, N Leal, LD Estrada, A Gonzalez, F Serrano, K Araya, ...
PloS one 9 (3), e92309, 2014
1032014
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