William DeGrado
William DeGrado
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β-Peptides: from structure to function
RP Cheng, SH Gellman, WF DeGrado
Chemical reviews 101 (10), 3219-3232, 2001
A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids
KT O'Neil, WF DeGrado
Science 250 (4981), 646-651, 1990
How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices
KT O'Neil, WF DeGrado
Trends in biochemical sciences 15 (2), 59-64, 1990
Foldamers as versatile frameworks for the design and evolution of function
CM Goodman, S Choi, S Shandler, WF DeGrado
Nature chemical biology 3 (5), 252-262, 2007
Characterization of a helical protein designed from first principles
L Regan, WF DeGrado
Science 241 (4868), 976-978, 1988
De novo design and structural characterization of proteins and metalloproteins
WF DeGrado, CM Summa, V Pavone, F Nastri, A Lombardi
Annual review of biochemistry 68 (1), 779-819, 1999
Protein design: a hierarchic approach
JW Bryson, SF Betz, HS Lu, DJ Suich, HX Zhou, KT O'Neil, WF DeGrado
Science 270 (5238), 935-941, 1995
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong
Nature 463 (7281), 689-692, 2010
Structural basis for the function and inhibition of an influenza virus proton channel
AL Stouffer, R Acharya, D Salom, AS Levine, L Di Costanzo, CS Soto, ...
Nature 451 (7178), 596-599, 2008
Synthetic amphiphilic peptide models for protein ion channels
JD Lear, ZR Wasserman, WF DeGrado
Science 240 (4856), 1177-1181, 1988
Protein design, a minimalist approach
WF DeGrado, ZR Wasserman, JD Lear
Science 243 (4891), 622-628, 1989
De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications
GN Tew, RW Scott, ML Klein, WF DeGrado
Accounts of chemical research 43 (1), 30-39, 2010
Design and synthesis of multi-haem proteins
DE Robertson, RS Farid, CC Moser, JL Urbauer, SE Mulholland, R Pidikiti, ...
Nature 368 (6470), 425-432, 1994
De novo design of biomimetic antimicrobial polymers
GN Tew, D Liu, B Chen, RJ Doerksen, J Kaplan, PJ Carroll, ML Klein, ...
Proceedings of the National Academy of Sciences 99 (8), 5110-5114, 2002
Amphiphilic polymethacrylate derivatives as antimicrobial agents
K Kuroda, WF DeGrado
Journal of the American Chemical Society 127 (12), 4128-4129, 2005
Short peptides self-assemble to produce catalytic amyloids
CM Rufo, YS Moroz, OV Moroz, J Stöhr, TA Smith, X Hu, WF DeGrado, ...
Nature chemistry 6 (4), 303-309, 2014
Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs
A Senes, DE Engel, WF DeGrado
Current opinion in structural biology 14 (4), 465-479, 2004
Induction of peptide conformation at apolar water interfaces. 1. A study with model peptides of defined hydrophobic periodicity
WF DeGrado, JD Lear
Journal of the American Chemical Society 107 (25), 7684-7689, 1985
De novo design of antibacterial beta-peptides
Y Hamuro, JP Schneider, WF DeGrado
Journal of the American Chemical Society 121 (51), 12200-12201, 1999
Asparagine-mediated self-association of a model transmembrane helix
C Choma, H Gratkowski, JD Lear, WF DeGrado
Nature structural biology 7 (2), 161-166, 2000
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