Fusion of TEL, the ETS-Variant Gene 6 (ETV6), to the Receptor-Associated Kinase JAK2 as a Result of t(9; 12) in a Lymphoid and t(9; 15; 12) in a Myeloid Leukemia P Peeters, SD Raynaud, J Cools, I Wlodarska, J Grosgeorge, P Philip, ... Blood, The Journal of the American Society of Hematology 90 (7), 2535-2540, 1997 | 619 | 1997 |
Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐and lymphoproliferative disease in mice by retrovirally transduced TEL … J Schwaller, J Frantsve, J Aster, IR Williams, MH Tomasson, TS Ross, ... The EMBO journal, 1998 | 325 | 1998 |
A genetics-led approach defines the drug target landscape of 30 immune-related traits H Fang, H De Wolf, B Knezevic, KL Burnham, J Osgood, A Sanniti, ... Nature genetics 51 (7), 1082-1091, 2019 | 190 | 2019 |
Fusion of ETV6 to MDS1/EVI1 as a Result of t(3;12)(q26;p13) in Myeloproliferative Disorders P Peeters, I Wlodarska, M Baens, A Criel, D Selleslag, A Hagemeijer, ... Cancer Research 57 (4), 564-569, 1997 | 189 | 1997 |
Variants in the FTO gene are associated with common obesity in the Belgian population A Peeters, S Beckers, A Verrijken, P Roevens, P Peeters, L Van Gaal, ... Molecular genetics and metabolism 93 (4), 481-484, 2008 | 187 | 2008 |
Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: a multi-site omics study V Volpato, J Smith, C Sandor, JS Ried, A Baud, A Handel, SE Newey, ... Stem cell reports 11 (4), 897-911, 2018 | 176 | 2018 |
Sustained synchronized neuronal network activity in a human astrocyte co-culture system J Kuijlaars, T Oyelami, A Diels, J Rohrbacher, S Versweyveld, ... Scientific reports 6 (1), 36529, 2016 | 172 | 2016 |
Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor B Brone, PJ Peeters, R Marrannes, M Mercken, R Nuydens, T Meert, ... Toxicology and applied pharmacology 231 (2), 150-156, 2008 | 141 | 2008 |
Essential role for TRPV1 in stress‐induced (mast cell‐dependent) colonic hypersensitivity in maternally separated rats RM Van Den Wijngaard, TK Klooker, O Welting, OI Stanisor, MM Wouters, ... Neurogastroenterology & Motility 21 (10), 1107-e94, 2009 | 138 | 2009 |
Genomic organization of TEL: The human ETS-variant gene 6. M Baens, P Peeters, C Guo, J Aerssens, P Marynen Genome Research 6 (5), 404-413, 1996 | 135 | 1996 |
Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project B Verbist, G Klambauer, L Vervoort, W Talloen, Z Shkedy, O Thas, ... Drug discovery today 20 (5), 505-513, 2015 | 114 | 2015 |
Association of SIRT1 gene variation with visceral obesity AV Peeters, S Beckers, A Verrijken, I Mertens, P Roevens, PJ Peeters, ... Human genetics 124, 431-436, 2008 | 108 | 2008 |
Evidence for position effects as a variantETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13) J Cools, N Mentens, MD Odero, P Peeters, I Wlodarska, M Delforge, ... Blood, The Journal of the American Society of Hematology 99 (5), 1776-1784, 2002 | 104 | 2002 |
Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice K Hillsley, JH Lin, A Stanisz, D Grundy, J Aerssens, PJ Peeters, ... The Journal of Physiology 576 (1), 257-267, 2006 | 88 | 2006 |
Using human iPSC-derived neurons to model TAU aggregation A Verheyen, A Diels, J Dijkmans, T Oyelami, G Meneghello, L Mertens, ... PloS one 10 (12), e0146127, 2015 | 78 | 2015 |
Translation of a tumor microenvironment mimicking 3D tumor growth co-culture assay platform to high-content screening E Krausz, R de Hoogt, E Gustin, F Cornelissen, T Grand-Perret, L Janssen, ... Journal of biomolecular screening 18 (1), 54-66, 2013 | 71 | 2013 |
Mammalian Navigators are microtubule plus‐end tracking proteins that can reorganize the cytoskeleton to induce neurite‐like extensions J van Haren, K Draegestein, N Keijzer, JP Abrahams, F Grosveld, ... Cell motility and the cytoskeleton 66 (10), 824-838, 2009 | 67 | 2009 |
JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations SN Chandrasekaran, J Ackerman, E Alix, DM Ando, J Arevalo, M Bennion, ... BioRxiv, 2023.03. 23.534023, 2023 | 65 | 2023 |
Genetically engineered iPSC-derived FTDP-17 MAPT neurons display mutation-specific neurodegenerative and neurodevelopmental phenotypes A Verheyen, A Diels, J Reumers, K Van Hoorde, I Van den Wyngaert, ... Stem cell reports 11 (2), 363-379, 2018 | 63 | 2018 |
Exploration and analysis of DNA microarray and other high-dimensional data D Amaratunga, J Cabrera, Z Shkedy John Wiley & Sons, 2014 | 62* | 2014 |