Manu Setty
Manu Setty
Assistant Professor, Fred Hutchinson Cancer Center
Dirección de correo verificada de - Página principal
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CSF-1R inhibition alters macrophage polarization and blocks glioma progression
SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ...
Nature medicine 19 (10), 1264-1272, 2013
Single-cell map of diverse immune phenotypes in the breast tumor microenvironment
E Azizi, AJ Carr, G Plitas, AE Cornish, C Konopacki, S Prabhakaran, ...
Cell 174 (5), 1293-1308. e36, 2018
Wishbone identifies bifurcating developmental trajectories from single-cell data
M Setty, MD Tadmor, S Reich-Zeliger, O Angel, TM Salame, P Kathail, ...
Nature biotechnology 34 (6), 637-645, 2016
Characterization of cell fate probabilities in single-cell data with Palantir
M Setty, V Kiseliovas, J Levine, A Gayoso, L Mazutis, D Pe’Er
Nature biotechnology 37 (4), 451-460, 2019
CellRank for directed single-cell fate mapping
M Lange, V Bergen, M Klein, M Setty, B Reuter, M Bakhti, H Lickert, ...
Nature methods 19 (2), 159-170, 2022
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells
EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ...
Nature biotechnology 29 (1), 73-78, 2011
Ibrutinib Resistance in Chronic Lymphocytic Leukemia
R Furman, P Lu, M Setty, A Perez, J Racchumi, G Xu, H Wu, J Ma, ...
New England Journal of Medicine, 2352-2354, 2014
The emergent landscape of the mouse gut endoderm at single-cell resolution
S Nowotschin, M Setty, YY Kuo, V Liu, V Garg, R Sharma, CS Simon, ...
Nature 569 (7756), 361-367, 2019
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ...
Nature genetics 43 (7), 673-678, 2011
Regenerative lineages and immune-mediated pruning in lung cancer metastasis
AM Laughney, J Hu, NR Campbell, SF Bakhoum, M Setty, VP Lavallée, ...
Nature medicine 26 (2), 259-269, 2020
Epigenomic-guided mass cytometry profiling reveals disease-specific features of exhausted CD8 T cells
B Bengsch, T Ohtani, O Khan, M Setty, S Manne, S O’Brien, PF Gherardini, ...
Immunity 48 (5), 1029-1045. e5, 2018
BCL6 positively regulates AID and germinal center gene expression via repression of miR-155
K Basso, C Schneider, Q Shen, AB Holmes, M Setty, C Leslie, ...
Journal of Experimental Medicine 209 (13), 2455-2465, 2012
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease
SR Guttikonda, L Sikkema, J Tchieu, N Saurat, RM Walsh, O Harschnitz, ...
Nature Neuroscience 24 (3), 343-354, 2021
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling
JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ...
Science 377 (6611), 1180-1191, 2022
Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma
M Setty, K Helmy, AA Khan, J Silber, A Arvey, F Neezen, P Agius, JT Huse, ...
Molecular systems biology 8 (1), 605, 2012
MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas
C Schneider, M Setty, AB Holmes, RL Maute, CS Leslie, L Mussolin, ...
Proceedings of the National Academy of Sciences 111 (22), 8185-8190, 2014
Negative co-stimulation constrains T cell differentiation by imposing boundaries on possible cell states
SC Wei, R Sharma, NAAS Anang, JH Levine, Y Zhao, JJ Mancuso, ...
Immunity 50 (4), 1084-1098. e10, 2019
Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation
AJ González, M Setty, CS Leslie
Nature genetics 47 (11), 1249-1259, 2015
SeqGL identifies context-dependent binding signals in genome-wide regulatory element maps
M Setty, CS Leslie
PLoS computational biology 11 (5), e1004271, 2015
Single-cell transcriptomics reveals early emergence of liver parenchymal and non-parenchymal cell lineages
J Lotto, S Drissler, R Cullum, W Wei, M Setty, EM Bell, SC Boutet, ...
Cell 183 (3), 702-716. e14, 2020
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Artículos 1–20