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Justin Ashworth
Justin Ashworth
Dirección de correo verificada de uw.edu - Página principal
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RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite
SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ...
PloS one 6 (6), e20161, 2011
5892011
Computational redesign of endonuclease DNA binding and cleavage specificity
J Ashworth, JJ Havranek, CM Duarte, D Sussman, RJ Monnat Jr, ...
Nature 441 (7093), 656-659, 2006
4282006
Rare variants in neuronal excitability genes influence risk for bipolar disorder
SA Ament, S Szelinger, G Glusman, J Ashworth, L Hou, N Akula, ...
Proceedings of the National Academy of Sciences 112 (11), 3576-3581, 2015
1892015
Mutations in NOTCH1 cause Adams-Oliver syndrome
AB Stittrich, A Lehman, DL Bodian, J Ashworth, Z Zong, H Li, P Lam, ...
The American Journal of Human Genetics 95 (3), 275-284, 2014
1862014
Genome-wide diel growth state transitions in the diatom Thalassiosira pseudonana
J Ashworth, S Coesel, A Lee, EV Armbrust, MV Orellana, NS Baliga
Proceedings of the National Academy of Sciences 110 (18), 7518-7523, 2013
1502013
Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs
J Ashworth, GK Taylor, JJ Havranek, SA Quadri, BL Stoddard, D Baker
Nucleic acids research 38 (16), 5601-5608, 2010
1292010
Exploitation of binding energy for catalysis and design
SB Thyme, J Jarjour, R Takeuchi, JJ Havranek, J Ashworth, ...
Nature 461 (7268), 1300-1304, 2009
1092009
Diatom acclimation to elevated CO2 via cAMP signalling and coordinated gene expression
GMM Hennon, J Ashworth, RD Groussman, C Berthiaume, RL Morales, ...
Nature Climate Change 5 (8), 761-765, 2015
872015
Assessment of the optimization of affinity and specificity at protein–DNA interfaces
J Ashworth, D Baker
Nucleic acids research 37 (10), e73-e73, 2009
542009
Phytosterol biosynthesis and production by diatoms (Bacillariophyceae)
AC Jaramillo-Madrid, J Ashworth, M Fabris, PJ Ralph
Phytochemistry 163, 46-57, 2019
372019
Reprogramming homing endonuclease specificity through computational design and directed evolution
SB Thyme, SJS Boissel, S Arshiya Quadri, T Nolan, DA Baker, RU Park, ...
Nucleic acids research 42 (4), 2564-2576, 2014
362014
Pan-transcriptomic analysis identifies coordinated and orthologous functional modules in the diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum
J Ashworth, S Turkarslan, M Harris, MV Orellana, NS Baliga
Marine Genomics 26, 21-28, 2016
312016
Evolution of context dependent regulation by expansion of feast/famine regulatory proteins
CL Plaisier, FY Lo, J Ashworth, AN Brooks, KD Beer, A Kaur, M Pan, ...
BMC systems biology 8, 1-14, 2014
282014
Thermodynamics of DNA target site recognition by homing endonucleases
JH Eastberg, AMC Smith, L Zhao, J Ashworth, BW Shen, BL Stoddard
Nucleic acids research 35 (21), 7209-7221, 2007
262007
A new mechanistic understanding of light-limitation in the seagrass Zostera muelleri
PA Davey, M Pernice, J Ashworth, U Kuzhiumparambil, M Szabó, ...
Marine environmental research 134, 55-67, 2018
242018
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics
RL Bateman, J Ashworth, JF Witte, LJ Baker, P Bhanumoorthy, DE Timm, ...
Biochemical Journal 402 (2), 251-260, 2007
242007
Levels of diatom minor sterols respond to changes in temperature and salinity
AC Jaramillo-Madrid, J Ashworth, PJ Ralph
Journal of Marine Science and Engineering 8 (2), 85, 2020
212020
The unique sterol biosynthesis pathway of three model diatoms consists of a conserved core and diversified endpoints
AC Jaramillo-Madrid, J Ashworth, M Fabris, PJ Ralph
Algal research 48, 101902, 2020
192020
Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals
AB Stittrich, J Ashworth, M Shi, M Robinson, D Mauldin, ME Brunkow, ...
Human genome variation 3 (1), 1-9, 2016
192016
Overexpression of Key Sterol Pathway Enzymes in Two Model Marine Diatoms Alters Sterol Profiles in Phaeodactylum tricornutum
AC Jaramillo-Madrid, R Abbriano, J Ashworth, M Fabris, M Pernice, ...
Pharmaceuticals 13 (12), 481, 2020
142020
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Artículos 1–20