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Yixuan J. Hou
Yixuan J. Hou
Moderna Therapeutics
Verified email at modernatx.com
Title
Cited by
Cited by
Year
SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ...
Cell 182 (2), 429-446. e14, 2020
14722020
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ...
Science 370 (6523), 1464-1468, 2020
9392020
The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
L Premkumar, B Segovia-Chumbez, R Jadi, DR Martinez, R Raut, ...
Science immunology 5 (48), eabc8413, 2020
8922020
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
KH Dinnon III, SR Leist, A Schäfer, CE Edwards, DR Martinez, ...
Nature 586 (7830), 560-566, 2020
6522020
A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2
AO Hassan, NM Kafai, IP Dmitriev, JM Fox, BK Smith, IB Harvey, RE Chen, ...
Cell 183 (1), 169-184. e13, 2020
4962020
A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
SR Leist, KH Dinnon, A Schäfer, VT Longping, K Okuda, YJ Hou, A West, ...
Cell 183 (4), 1070-1085. e12, 2020
4882020
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
Science 371 (6531), 823-829, 2021
2842021
Genomic RNA elements drive phase separation of the SARS-CoV-2 nucleocapsid
C Iserman, CA Roden, MA Boerneke, RSG Sealfon, GA McLaughlin, ...
Molecular cell 80 (6), 1078-1091. e6, 2020
2592020
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
WN Voss, YJ Hou, NV Johnson, G Delidakis, JE Kim, K Javanmardi, ...
Science 372 (6546), 1108-1112, 2021
2382021
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2
TW Linsky, R Vergara, N Codina, JW Nelson, MJ Walker, W Su, ...
Science 370 (6521), 1208-1214, 2020
1892020
Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection
CE Edwards, BL Yount, RL Graham, SR Leist, YJ Hou, KH Dinnon III, ...
Proceedings of the National Academy of Sciences 117 (43), 26915-26925, 2020
1182020
Comparison of subgenomic and total RNA in SARS-CoV-2-challenged rhesus macaques
G Dagotto, NB Mercado, DR Martinez, YJ Hou, JP Nkolola, RH Carnahan, ...
Journal of virology 95 (8), 10.1128/jvi. 02370-20, 2021
1022021
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome
K Zhang, IN Zheludev, RJ Hagey, R Haslecker, YJ Hou, R Kretsch, ...
Nature Structural & Molecular Biology 28 (9), 747-754, 2021
912021
Characterization of a pathogenic full-length cDNA clone and transmission model for porcine epidemic diarrhea virus strain PC22A
A Beall, B Yount, CM Lin, Y Hou, Q Wang, L Saif, R Baric
MBio 7 (1), 10.1128/mbio. 01451-15, 2016
882016
Deletion of a 197-amino-acid region in the N-terminal domain of spike protein attenuates porcine epidemic diarrhea virus in piglets
Y Hou, CM Lin, M Yokoyama, BL Yount, D Marthaler, AL Douglas, ...
Journal of virology 91 (14), 10.1128/jvi. 00227-17, 2017
832017
Evaluation of cell-based and surrogate SARS-CoV-2 neutralization assays
AM Sholukh, A Fiore-Gartland, ES Ford, MD Miner, YJ Hou, LV Tse, ...
Journal of Clinical Microbiology 59 (10), 10.1128/jcm. 00527-21, 2021
792021
Deletion of both the tyrosine-based endocytosis signal and the endoplasmic reticulum retrieval signal in the cytoplasmic tail of spike protein attenuates porcine epidemic …
Y Hou, T Meulia, X Gao, LJ Saif, Q Wang
Journal of virology 93 (2), 10.1128/jvi. 01758-18, 2019
532019
Genetic evolution analysis and pathogenicity assessment of porcine epidemic diarrhea virus strains circulating in part of China during 2011–2017
P Chen, K Wang, Y Hou, H Li, X Li, L Yu, Y Jiang, F Gao, W Tong, H Yu, ...
Infection, Genetics and Evolution 69, 153-165, 2019
522019
Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage
CM Lin, Y Hou, DG Marthaler, X Gao, X Liu, L Zheng, LJ Saif, Q Wang
Veterinary microbiology 201, 62-71, 2017
492017
Emerging highly virulent porcine epidemic diarrhea virus: molecular mechanisms of attenuation and rational design of live attenuated vaccines
Y Hou, Q Wang
International journal of molecular sciences 20 (21), 5478, 2019
392019
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