Jacqueline Amanda Shaw
Jacqueline Amanda Shaw
Head Department of Genetics and Genome Biology, Professor of Translational Cancer Genetics
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Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
Neoantigen-directed immune escape in lung cancer evolution
R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ...
Nature 567 (7749), 479-485, 2019
Methylation associated inactivation of RASSF1A from region 3p21. 3 in lung, breast and ovarian tumours
A Agathanggelou, S Honorio, DP Macartney, A Martinez, A Dallol, ...
Oncogene 20 (12), 1509-1518, 2001
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation
AS Whale, JF Huggett, S Cowen, V Speirs, J Shaw, S Ellison, CA Foy, ...
Nucleic acids research 40 (11), e82-e82, 2012
Mapping of mutation causing Friedreich's ataxia to human chromosome 9
S Chamberlain, J Shaw, A Rowland, J Wallis, S South, Y Nakamura, ...
Nature 334 (6179), 248-250, 1988
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence
RC Coombes, K Page, R Salari, RK Hastings, A Armstrong, S Ahmed, ...
Clinical Cancer Research 25 (14), 4255-4263, 2019
Tracking genomic cancer evolution for precision medicine: the lung TRACERx study
M Jamal-Hanjani, A Hackshaw, Y Ngai, J Shaw, C Dive, S Quezada, ...
PLoS biology 12 (7), e1001906, 2014
A framework for the development of effective anti-metastatic agents
RL Anderson, T Balasas, J Callaghan, RC Coombes, J Evans, JA Hall, ...
Nature Reviews Clinical Oncology 16 (3), 185-204, 2019
Genomic analysis of circulating cell-free DNA infers breast cancer dormancy
JA Shaw, K Page, K Blighe, N Hava, D Guttery, B Ward, J Brown, ...
Genome research 22 (2), 220-231, 2012
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
LQJ AbdulJabbar K, Raza SEA, Rosenthal R, Jamal-Hanjani M, Veeriah S, Akarca ...
Nat Med 26 (7), 1054-1062, 2020
Mutation analysis of cell-free DNA and single circulating tumor cells in metastatic breast cancer patients with high circulating tumor cell counts
JA Shaw, DS Guttery, A Hills, D Fernandez-Garcia, K Page, BM Rosales, ...
Clinical Cancer Research 23 (1), 88-96, 2017
Influence of plasma processing on recovery and analysis of circulating nucleic acids
K Page, DS Guttery, N Zahra, L Primrose, SR Elshaw, JH Pringle, ...
PloS one 8 (10), e77963, 2013
Glomerular expression of nephrin is decreased in acquired human nephrotic syndrome.
PN Furness, LL Hall, JA Shaw, JH Pringle
Nephrology, dialysis, transplantation: official publication of the European …, 1999
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution
JHM López S, Lim EL, Horswell S, Haase K, Huebner A, Dietzen M, Mourikis TP ...
Nat Genet. 52 (3), 283-293, 2020
Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor–Positive Metastatic Breast Cancer
DS Guttery, K Page, A Hills, L Woodley, SD Marchese, B Rghebi, ...
Clinical chemistry 61 (7), 974-982, 2015
Lung adenocarcinoma promotion by air pollutants
W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ...
Nature 616 (7955), 159-167, 2023
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