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Naveen Thakur
Naveen Thakur
Bristol Myers Squibb
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Anionic phospholipids control mechanisms of GPCR-G protein recognition
N Thakur, AP Ray, L Sharp, B Jin, A Duong, NG Pour, S Obeng, ...
Nature Communications 14 (1), 794, 2023
202023
Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered
S Wei, N Thakur, AP Ray, B Jin, S Obeng, CR McCurdy, LR McMahon, ...
Structure 30 (3), 329-337. e5, 2022
182022
Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence spectroscopy
N Thakur, S Wei, AP Ray, R Lamichhane, MT Eddy
STAR Protocols 3 (3), 101535, 2022
132022
Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition
AP Ray, N Thakur, NG Pour, MT Eddy
Structure 31 (7), 836-847. e6, 2023
102023
Global insights into the fine tuning of human A2AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR
G Ferré, K Anazia, LO Silva, AP Thakur, Naveen: Ray, MT Eddy
Cell Reports 41 (12), 111844, 2022
62022
Single-molecule visualization of human A2A adenosine receptor activation by a G protein and constitutively activating mutations
S Wei, NG Pour, S Tiruvadi-Krishnan, AP Ray, N Thakur, MT Eddy, ...
Communications Biology 6 (1), 1218, 2023
22023
Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
B Jin, N Thakur, AV Wijesekara, MT Eddy
Current Opinion in Pharmacology, 102364, 2023
22023
Membrane mimetic dependence of GPCR energy landscapes
N Thakur, AP Ray, ER Lyman, ZG Gao, KA Jacobson, MT Eddy
Biophysical Journal 123 (3), 482a, 2024
12024
A comparative study of interfacial environments in lipid nanodiscs and vesicles
X You, N Thakur, AP Ray, MT Eddy, CR Baiz
Biophysical reports 2 (3), 2022
12022
Silver Triflate Catalyzed Domino Reactions of o‐Alkynylanilines: An Approach Toward Unsymmetrical Diarylacetates and Triarylmethanes
SD Jadhav, T Singh, N Thakur, A Singh
Asian Journal of Organic Chemistry 11 (5), e202200011, 2022
12022
A2A adenosine receptor conformational dynamics revealed by single-molecule fluorescence
S Wei, N Thakur, AP Ray, B Jin, S Obeng, CR McCurdy, LR McMahon, ...
Biophysical Journal 121 (3), 193a, 2022
12022
Single-molecule view of slow and sequential conformational transitions of A2A adenosine receptor
S Wei, N Thakur, AP Ray, B Jin, S Obeng, CR McCurdy, LR McMahon, ...
Biophysical Journal 121 (3), 429a, 2022
12022
Visualizing the structural dynamics of G protein-activated A2A adenosine receptor at the single-molecule level
S Wei, NG Pour, ST Krishnan, AP Ray, N Thakur, R Lamichhane, ...
Biophysical Journal 123 (3), 172a, 2024
2024
Uncovering the structural mechanisms of how constitutively activating mutations alter GPCR function
NG Pour, S Wei, ST Krishnan, AP Ray, N Thakur, MT Eddy, ...
Biophysical Journal 123 (3), 65a, 2024
2024
Phosphatidyl serine preconditions the A2AAR for G-protein coupling via a conserved motif on TM6 and TM7
LM Sharp, MT Eddy, N Thakur, AP Ray, ER Lyman
Biophysical Journal 122 (3), 510a-511a, 2023
2023
Regulation of human A2A adenosine receptor conformational dynamics by endogenous phospholipids
N Thakur, AP Ray, L Sharp, NG Pour, ZG Gao, S Obeng, B Jin, ...
Biophysical Journal 121 (3), 194a, 2022
2022
Structural Insights into Activation of a Human G Protein‐Coupled Receptor by Membrane Phospholipids
M Eddy, N Thakur, A Ray, A Duong, B Jin
The FASEB Journal 35, 2021
2021
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Artículos 1–17