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Michael Rusch
Michael Rusch
Director of Bioinformatics Software Development, St. Jude Children's Research Hospital
Dirección de correo verificada de stjude.org
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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157-163, 2012
17902012
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner, RC Harvey, YL Yang, D Pei, ...
New England journal of medicine 371 (11), 1005-1015, 2014
14772014
Germline mutations in predisposition genes in pediatric cancer
J Zhang, MF Walsh, G Wu, MN Edmonson, TA Gruber, J Easton, ...
New England Journal of Medicine 373 (24), 2336-2346, 2015
12242015
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Nature genetics 46 (5), 444-450, 2014
10352014
Novel mutations target distinct subgroups of medulloblastoma
G Robinson, M Parker, TA Kranenburg, C Lu, X Chen, L Ding, TN Phoenix, ...
Nature 488 (7409), 43-48, 2012
9172012
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
Y Liu, J Easton, Y Shao, J Maciaszek, Z Wang, MR Wilkinson, ...
Nature genetics 49 (8), 1211-1218, 2017
8062017
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
Nature genetics 45 (6), 602-612, 2013
7862013
The genomic landscape of hypodiploid acute lymphoblastic leukemia
L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ...
Nature genetics 45 (3), 242-252, 2013
7852013
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
X Ma, YU Liu, Y Liu, LB Alexandrov, MN Edmonson, C Gawad, X Zhou, ...
Nature 555 (7696), 371-376, 2018
7212018
Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma
X Chen, A Bahrami, A Pappo, J Easton, J Dalton, E Hedlund, D Ellison, ...
Cell reports 7 (1), 104-112, 2014
6752014
C11orf95RELA fusions drive oncogenic NF-κB signalling in ependymoma
M Parker, KM Mohankumar, C Punchihewa, R Weinlich, JD Dalton, Y Li, ...
Nature 506 (7489), 451-455, 2014
6632014
CREST maps somatic structural variation in cancer genomes with base-pair resolution
J Wang, CG Mullighan, J Easton, S Roberts, SL Heatley, J Ma, MC Rusch, ...
Nature methods 8 (8), 652-654, 2011
5612011
A novel retinoblastoma therapy from genomic and epigenetic analyses
J Zhang, CA Benavente, J McEvoy, J Flores-Otero, L Ding, X Chen, ...
Nature 481 (7381), 329-334, 2012
5562012
Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations
F Tirode, D Surdez, X Ma, M Parker, MC Le Deley, A Bahrami, Z Zhang, ...
Cancer discovery 4 (11), 1342-1353, 2014
5112014
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
AK Andersson, J Ma, J Wang, X Chen, AL Gedman, J Dang, J Nakitandwe, ...
Nature genetics 47 (4), 330-337, 2015
4792015
Vismodegib exerts targeted efficacy against recurrent sonic hedgehog–subgroup medulloblastoma: results from phase II pediatric brain tumor consortium studies PBTC-025B and PBTC-032
GW Robinson, BA Orr, G Wu, S Gururangan, T Lin, I Qaddoumi, ...
Journal of Clinical Oncology 33 (24), 2646, 2015
4612015
Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia
X Ma, M Edmonson, D Yergeau, DM Muzny, OA Hampton, M Rusch, ...
Nature communications 6 (1), 6604, 2015
4512015
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
R Huether, L Dong, X Chen, G Wu, M Parker, L Wei, J Ma, MN Edmonson, ...
Nature communications 5 (1), 3630, 2014
4072014
Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
I Qaddoumi, W Orisme, J Wen, T Santiago, K Gupta, JD Dalton, B Tang, ...
Acta neuropathologica 131, 833-845, 2016
3602016
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
S Shah, KA Schrader, E Waanders, AE Timms, J Vijai, C Miething, ...
Nature genetics 45 (10), 1226-1231, 2013
3392013
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Artículos 1–20