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Benjamin J Ainscough
Benjamin J Ainscough
Dirección de correo verificada de go.wustl.edu - Página principal
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Convergent loss of PTEN leads to clinical resistance to a PI (3) Kα inhibitor
D Juric, P Castel, M Griffith, OL Griffith, HH Won, H Ellis, SH Ebbesen, ...
Nature 518 (7538), 240-244, 2015
5732015
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ...
Nature genetics 49 (2), 170-174, 2017
5222017
DGIdb 2.0: mining clinically relevant drug–gene interactions
AH Wagner, AC Coffman, BJ Ainscough, NC Spies, ZL Skidmore, ...
Nucleic acids research 44 (D1), D1036-D1044, 2016
3812016
High-performance web services for querying gene and variant annotation
J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ...
Genome biology 17, 1-7, 2016
1812016
Informatics for RNA sequencing: a web resource for analysis on the cloud
M Griffith, JR Walker, NC Spies, BJ Ainscough, OL Griffith
PLoS computational biology 11 (8), e1004393, 2015
1562015
Genome-wide association study of CSF levels of 59 Alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation
JSK Kauwe, MH Bailey, PG Ridge, R Perry, ME Wadsworth, KL Hoyt, ...
PLoS genetics 10 (10), e1004758, 2014
1332014
The prognostic effects of somatic mutations in ER-positive breast cancer
OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ...
Nature communications 9 (1), 3476, 2018
1252018
DoCM: a database of curated mutations in cancer
BJ Ainscough, M Griffith, AC Coffman, AH Wagner, J Kunisaki, ...
Nature methods 13 (10), 806-807, 2016
1102016
Organizing knowledge to enable personalization of medicine in cancer
BM Good, BJ Ainscough, JF McMichael, AI Su, OL Griffith
Genome biology 15, 1-9, 2014
1012014
Genome modeling system: a knowledge management platform for genomics
M Griffith, OL Griffith, SM Smith, A Ramu, MB Callaway, AM Brummett, ...
PLoS computational biology 11 (7), e1004274, 2015
882015
Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid
O Harari, C Cruchaga, JSK Kauwe, BJ Ainscough, K Bales, EH Pickering, ...
Biological psychiatry 75 (9), 723-731, 2014
792014
Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples
EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, LM Sheta, ...
Genetics in Medicine 21 (4), 972-981, 2019
752019
A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data
BJ Ainscough, EK Barnell, P Ronning, KM Campbell, AH Wagner, ...
Nature genetics 50 (12), 1735-1743, 2018
712018
Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia
M Griffith, OL Griffith, K Krysiak, ZL Skidmore, MJ Christopher, JM Klco, ...
Experimental hematology 44 (7), 603-613, 2016
542016
Molecular phylogenetics of the burrowing crayfish genus Fallicambarus (Decapoda: Cambaridae)
BJ Ainscough, JW Breinholt, HW Robison, KA Crandall
Zoologica Scripta 42 (3), 306-316, 2013
272013
CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase
K Krysiak, AM Danos, J Saliba, JF McMichael, AC Coffman, S Kiwala, ...
Nucleic acids research 51 (D1), D1230-D1241, 2023
92023
CIViC: a knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer
M Griffith, NC Spies, K Krysiak, AC Coffman, JF McMichael, BJ Ainscough, ...
bioRxiv, 072892, 2016
72016
MyGene. info and MyVariant. info: gene and variant annotation query services
J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ...
bioRxiv, 035667, 2015
42015
A community approach to the cancer-variant-interpretation bottleneck
K Krysiak, AM Danos, S Kiwala, JF McMichael, AC Coffman, EK Barnell, ...
Nature cancer 3 (5), 522-525, 2022
32022
Knowledge Driven Approaches and Machine Learning Improve the Identification of Clinically Relevant Somatic Mutations in Cancer Genomics
BJ Ainscough
Washington University in St. Louis, 2017
12017
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Artículos 1–20