| Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites MD Olp, DJ Sprague, CJ Goetz, SG Kathman, SL Wynia-Smith, ... ACS chemical biology 15 (4), 1036-1049, 2020 | 36 | 2020 |
| Enantio-and periselective nitroalkene Diels–Alder reaction MJ Narcis, DJ Sprague, B Captain, N Takenaka Organic & biomolecular chemistry 10 (46), 9134-9136, 2012 | 26 | 2012 |
| Diastereo-and enantioselective additions of α-nitro esters to imines for anti-α, β-diamino acid synthesis with α-alkyl-substitution DJ Sprague, A Singh, JN Johnston Chemical Science 9 (8), 2336-2339, 2018 | 21 | 2018 |
| Adaptation of a small-molecule hydrogen-bond donor catalyst to an enantioselective hetero-Diels–Alder reaction hypothesized for brevianamide biosynthesis DJ Sprague, BM Nugent, RA Yoder, BA Vara, JN Johnston Organic letters 17 (4), 880-883, 2015 | 16 | 2015 |
| Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity CM Rohr, DJ Sprague, SK Park, NJ Malcolm, JS Marchant Proceedings of the National Academy of Sciences 120 (1), e2217732120, 2023 | 15 | 2023 |
| Substituted Imidazoline Synthesis: A Diastereo-and Enantioselective aza-Henry Route to a Human Proteasome Modulator DJ Sprague, JN Johnston Organic letters 22 (21), 8496-8499, 2020 | 9 | 2020 |
| Mu-opioid receptor selective superagonists produce prolonged respiratory depression NJ Malcolm, B Palkovic, DJ Sprague, MM Calkins, JK Lanham, ... Iscience 26 (7), 2023 | 7 | 2023 |
| Development of activity-based probes for the protein deacylase Sirt1 CJ Goetz, DJ Sprague, BC Smith Bioorganic chemistry 104, 104232, 2020 | 7 | 2020 |
| Count on it! accurately measured respiratory rate is associated with lung function and clinical severity in children with acute asthma exacerbations DH Arnold, C Penrod, DJ Sprague, TV Hartert The Journal of pediatrics 175, 236, 2016 | 6 | 2016 |
| Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin M AbuEid, RF Keyes, D McAllister, F Peterson, IP Kadamberi, DJ Sprague, ... Iscience 25 (12), 2022 | 4 | 2022 |
| The anthelmintic meclonazepam activates a schistosome transient receptor potential channel SK Park, DJ Sprague, CM Rohr, EG Chulkov, I Petrow, S Kumar, ... Journal of Biological Chemistry 300 (1), 2024 | 3 | 2024 |
| Target-based discovery of a broad spectrum flukicide DJ Sprague, SK Park, S Gramberg, L Bauer, CM Rohr, EG Chulkov, ... bioRxiv, 2023 | 3 | 2023 |
| Molecular and cellular basis of praziquantel action in the cardiovascular system NA Yahya, JK Lanham, DJ Sprague, O Palygin, JD McCorvy, JS Marchant American Journal of Physiology-Cell Physiology 324 (2), C573-C587, 2023 | 3 | 2023 |
| Trisubstituted 1, 3, 5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12 DJ Sprague, AE Getschman, TG Fenske, BF Volkman, BC Smith ACS Medicinal Chemistry Letters 12 (11), 1773-1782, 2021 | 3 | 2021 |
| The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure–Activity Relationships at TRPMPZQ Orthologs DJ Sprague, M Kaethner, SK Park, CM Rohr, JL Harris, D Maillard, ... ACS medicinal chemistry letters 14 (11), 1537-1543, 2023 | 2 | 2023 |
| Diastereo-and enantioselective additions of [a]-nitro esters to imines for anti-[a],[b]-diamino acid synthesis with [a]-alkyl-substitution DJ Sprague, A Singh, JN Johnston Chem. Sci 9, 2336, 2018 | 2 | 2018 |
| Identification of a dihydropyridine scaffold that blocks ryanodine receptors GS Gunaratne, RT Rebbeck, LM McGurran, Y Yan, T Arzua, T Frolkis, ... Iscience 25 (1), 2022 | 1 | 2022 |
| Discovering and exploiting selectivity in BET tandem bromodomain recognition of epigenetic lysine acylation BC Smith, MD Olp, DJ Sprague The FASEB Journal 32, 524.15-524.15, 2018 | 1 | 2018 |
| Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types RA Jones Lipinski, JS Stancill, R Nuñez, SL Wynia-Smith, DJ Sprague, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2024 | | 2024 |
| TRP drop, TRP drop: a steady patter of anti-schistosomal target illumination DJ Sprague, CM Rohr, JS Marchant Frontiers in Parasitology 3, 1349623, 2024 | | 2024 |
