Evolutionary dynamics of neoantigens in growing tumors E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, L Zapata, ... Nature genetics 52 (10), 1057-1066, 2020 | 88 | 2020 |
Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 80 | 2022 |
The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022 | 58 | 2022 |
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues C Gabbutt, RO Schenck, DJ Weisenberger, C Kimberley, A Berner, ... Nature biotechnology 40 (5), 720-730, 2022 | 30 | 2022 |
Integrated quality control of allele-specific copy numbers, mutations and tumour purity from cancer whole genome sequencing assays J Househam, R Bergamin, S Milite, N Calonaci, A Antonello, MJ Williams, ... bioRxiv, 2021.02. 13.429885, 2022 | 9* | 2022 |
Factor VIII cross-matches to the human proteome reduce the predicted inhibitor risk in missense mutation hemophilia A DP Hart, N Uzun, S Skelton, A Kakoschke, J Househam, DS Moss, ... haematologica 104 (3), 599, 2019 | 8 | 2019 |
Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... bioRxiv, 2022.11. 16.515599, 2022 | 4 | 2022 |
Phenotypic noise and plasticity in cancer evolution FJH Whiting, J Househam, AM Baker, A Sottoriva, TA Graham Trends in Cell Biology, 2023 | 3 | 2023 |
Computational validation of clonal and subclonal copy number alterations from bulk tumor sequencing using CNAqc A Antonello, R Bergamin, N Calonaci, J Househam, S Milite, MJ Williams, ... Genome Biology 25 (1), 1-40, 2024 | 1 | 2024 |
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma M Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Salié, ... Research Square, 2023 | 1 | 2023 |
Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions I Tomlinson, A Cornish, A Gruber, R Houlston, A Sud, P Law, E Lakatos, ... | 1 | 2022 |
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, C Kimberley, ... bioRxiv, 2021.07. 14.451265, 2021 | 1 | 2021 |
Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma B Bátai, L Kiss, L Varga, Á Nagy, J Househam, AM Baker, T László, ... Modern Pathology 37 (5), 100465, 2024 | | 2024 |
Large-scale, low-cost, and accurate measurement of cancer evolutionary dynamics from clinical patient samples C Gabbutt, M Duran-Ferrer, H Grant, D Mallo, F Nadeu, J Househam, ... Cancer Research 84 (6_Supplement), 4300-4300, 2024 | | 2024 |
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer E Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ... bioRxiv, 2024.02. 12.579956, 2024 | | 2024 |
Spatially resolving the dynamics of immunoediting in advanced colorectal cancer V Gunasri, N Trahearn, E Lakatos, J Househam, T Heide, GD Cresswell, ... JOURNAL OF PATHOLOGY 261, S29-S29, 2023 | | 2023 |
Evolutionary dynamics of 1,976 lymphoid malignancies predict clinical outcome C Gabbutt, M Duran-Ferrer, H Grant, D Mallo, F Nadeu, J Househam, ... medRxiv, 2023.11. 10.23298336, 2023 | | 2023 |
O44 Co-evolution of mismatch repair loss and the immune response in Lynch Syndrome O Swinyard, AM Baker, K Monahan, M Jansen, C Gabbutt, C Kimberley, ... Gut 72 (Suppl 2), A25-A26, 2023 | | 2023 |
O47 Spatially resolving the dynamics of immune escape in advanced colorectal cancer V Gunasri, E Lakatos, N Trahearn, L Cisneros, J Househam, T Heide, ... Gut 72 (Suppl 2), A27-A27, 2023 | | 2023 |
253e IMMUNE EDITING IN THE INVASIVE MARGIN AND NODE DEPOSITS OF COLORECTAL CANCER SELECTS FOR CELLULAR NEIGHBOURHOODS ENRICHED IN PDL1+ CANCER CELLS V Gunasri, E Lakatos, N Trahearn, L Cisneros, J Househam, T Heide, ... Gastroenterology 164 (6), S-1569, 2023 | | 2023 |