Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum SC Bendall, EF Simonds, P Qiu, ED Amir, PO Krutzik, R Finck, ... Science 332 (6030), 687-696, 2011 | 2408 | 2011 |
Foxp3 transcription-factor-dependent and-independent regulation of the regulatory T cell transcriptional signature JA Hill, M Feuerer, K Tash, S Haxhinasto, J Perez, R Melamed, D Mathis, ... Immunity 27 (5), 786-800, 2007 | 766 | 2007 |
A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk DR Blair, CS Lyttle, JM Mortensen, CF Bearden, AB Jensen, ... Cell 155 (1), 70-80, 2013 | 248 | 2013 |
Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation R Obst, HM van Santen, R Melamed, AO Kamphorst, C Benoist, D Mathis Proceedings of the National Academy of Sciences 104 (39), 15460-15465, 2007 | 100 | 2007 |
FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm IT Aydin, RD Melamed, SJ Adams, M Castillo-Martin, A Demir, D Bryk, ... Journal of the National Cancer Institute 106 (6), dju107, 2014 | 93 | 2014 |
Gene expression microarrays: glimpses of the immunological genome G Hyatt, R Melamed, R Park, R Seguritan, C Laplace, L Poirot, S Zucchelli, ... Nature immunology 7 (7), 686-691, 2006 | 87 | 2006 |
Genomic characterization of dysplastic nevi unveils implications for diagnosis of melanoma RD Melamed, IT Aydin, GS Rajan, R Phelps, DN Silvers, KJ Emmett, ... Journal of Investigative Dermatology 137 (4), 905-909, 2017 | 63 | 2017 |
The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription ES Venanzi, R Melamed, D Mathis, C Benoist Proceedings of the National Academy of Sciences 105 (41), 15860-15865, 2008 | 59 | 2008 |
Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes RD Melamed, KJ Emmett, C Madubata, A Rzhetsky, R Rabadan Nature communications 6 (1), 7033, 2015 | 44 | 2015 |
Data-driven discovery of seasonally linked diseases from an Electronic Health Records system RD Melamed, H Khiabanian, R Rabadan BMC bioinformatics 15, 1-10, 2014 | 38 | 2014 |
GAB2 induces tumor angiogenesis in NRAS-driven melanoma Y Yang, J Wu, A Demir, M Castillo-Martin, RD Melamed, G Zhang, ... Oncogene 32 (31), 3627-3637, 2013 | 31 | 2013 |
An information theoretic method to identify combinations of genomic alterations that promote glioblastoma RD Melamed, J Wang, A Iavarone, R Rabadan Journal of molecular cell biology 7 (3), 203-213, 2015 | 16 | 2015 |
Patchwork of contrasting medication cultures across the USA RD Melamed, A Rzhetsky Nature Communications 9 (1), 1-12, 2018 | 5 | 2018 |
Using indication embeddings to represent patient health for drug safety studies RD Melamed JAMIA open 3 (3), 422-430, 2020 | 4 | 2020 |
Effects of Antidepressants on COVID-19 Outcomes: Retrospective Study on Large-Scale Electronic Health Record Data MM Rahman, AM Mahi, R Melamed, MAU Alam Interactive Journal of Medical Research 12 (1), e39455, 2023 | 1 | 2023 |
Shared etiology of Mendelian and complex disease supports drug discovery PN Lalagkas, RD Melamed | | 2024 |
Mapping drug biology to disease genetics to discover drug impacts on the human phenome M Habib, PN Lalagkas, RD Melamed Bioinformatics Advances 4 (1), vbae038, 2024 | | 2024 |
Mendelian disease comorbidity as a resource for novel therapeutic targets PN Lalakgas, RD Melamed bioRxiv, 2023.07. 23.550190, 2023 | | 2023 |
Drug-combination wide association studies of cancer PN Lalagkas, RD Melamed medRxiv, 2022.09. 29.22280479, 2022 | | 2022 |
Mining patterns in genomic and clinical cancer data to characterize novel driver genes RD Melamed Columbia University, 2015 | | 2015 |