| Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial RL Gottlieb, A Nirula, P Chen, J Boscia, B Heller, J Morris, G Huhn, ... Jama 325 (7), 632-644, 2021 | 1000 | 2021 |
| Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides M Koistinaho, S Lin, XIN Wu, M Esterman, D Koger, J Hanson, R Higgs, ... Nature medicine 10 (7), 719-726, 2004 | 700 | 2004 |
| Bamlanivimab plus etesevimab in mild or moderate Covid-19 M Dougan, A Nirula, M Azizad, B Mocherla, RL Gottlieb, P Chen, C Hebert, ... New England Journal of Medicine 385 (15), 1382-1392, 2021 | 646 | 2021 |
| Characteristic physical properties and structural fragments of marketed oral drugs M Vieth, MG Siegel, RE Higgs, IA Watson, DH Robertson, KA Savin, ... Journal of medicinal chemistry 47 (1), 224-232, 2004 | 434 | 2004 |
| The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ... Science translational medicine 13 (593), eabf1906, 2021 | 395 | 2021 |
| LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 344 | 2022 |
| Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients J Stebbing, V Krishnan, S de Bono, S Ottaviani, G Casalini, ... EMBO molecular medicine 12 (8), e12697, 2020 | 284 | 2020 |
| Comprehensive label-free method for the relative quantification of proteins from biological samples E Richard, MD Knierman, V Gelfanova, JP Butler, JE Hale Journal of proteome research 4 (4), 1442-1450, 2005 | 276 | 2005 |
| Kinomics—structural biology and chemogenomics of kinase inhibitors and targets M Vieth, RE Higgs, DH Robertson, M Shapiro, EA Gragg, H Hemmerle Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 243-257, 2004 | 254 | 2004 |
| Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations IB McInnes, NL Byers, RE Higgs, J Lee, WL Macias, S Na, RA Ortmann, ... Arthritis research & therapy 21, 1-10, 2019 | 229 | 2019 |
| Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma EY Zhen, RE Higgs, JA Gutierrez Analytical biochemistry 442 (1), 1-9, 2013 | 170 | 2013 |
| Identification of druggable cancer driver genes amplified across TCGA datasets Y Chen, J McGee, X Chen, TN Doman, X Gong, Y Zhang, N Hamm, X Ma, ... PloS one 9 (5), e98293, 2014 | 163 | 2014 |
| Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19 JT Sims, V Krishnan, CY Chang, SM Engle, G Casalini, GH Rodgers, ... Journal of Allergy and Clinical Immunology 147 (1), 107-111, 2021 | 162 | 2021 |
| Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry JF Kellie, RE Higgs, JW Ryder, A Major, TG Beach, CH Adler, K Merchant, ... Scientific reports 4 (1), 5797, 2014 | 161 | 2014 |
| LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ... BioRxiv, 2020.09. 30.318972, 2020 | 150 | 2020 |
| Experimental designs for selecting molecules from large chemical databases RE Higgs, KG Bemis, IA Watson, JH Wikel Journal of chemical information and computer sciences 37 (5), 861-870, 1997 | 126 | 1997 |
| M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine JM Witkin, C Overshiner, X Li, JT Catlow, GN Wishart, DA Schober, ... Journal of Pharmacology and Experimental Therapeutics 351 (2), 448-456, 2014 | 112 | 2014 |
| System and methods for qualitatively and quantitatively comparing complex admixtures using single ion chromatograms derived from spectroscopic analysis of such admixtures RE Higgs Jr, RK Julian Jr, RE Kaiser Jr US Patent 5,885,841, 1999 | 98 | 1999 |
| Advantages of raloxifene over alendronate or estrogen on nonreproductive and reproductive tissues in the long-term dosing of ovariectomized rats. M Sato, HU Bryant, P Iversen, J Helterbrand, F Smietana, K Bemis, ... Journal of Pharmacology and Experimental Therapeutics 279 (1), 298-305, 1996 | 96 | 1996 |
| Rapid method to estimate the presence of secondary metabolites in microbial extracts RE Higgs, JA Zahn, JD Gygi, MD Hilton Applied and environmental microbiology 67 (1), 371-376, 2001 | 95 | 2001 |
Guilherme RochaEli Lilly and CompanyVerified email at lilly.com
