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David Acevedo
David Acevedo
Chemist, FDA/CDER/OPQ
Dirección de correo verificada de fda.hhs.gov
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Evaluation of Mixed Suspension Mixed Product Removal Crystallization Processes Coupled with a Continuous Filtration System
D Acevedo, R Peña, Y Yang, A Barton, P Firth, ZK Nagy
Chemical Engineering and Processing: Process Intensification, 2016
592016
Multiobjective optimization of an unseeded batch cooling crystallizer for shape and size manipulation
D Acevedo, Y Tandy, ZK Nagy
Industrial & Engineering Chemistry Research 54 (7), 2156-2166, 2015
562015
Risk considerations on developing a continuous crystallization system for carbamazepine
X Yang, D Acevedo, A Mohammad, N Pavurala, H Wu, AL Brayton, ...
Organic Process Research & Development 21 (7), 1021-1033, 2017
542017
Near infrared method development for a continuous manufacturing blending process
YM Colón, MA Florian, D Acevedo, R Méndez, RJ Romañach
Journal of Pharmaceutical Innovation 9, 291-301, 2014
532014
Systematic classification of unseeded batch crystallization systems for achievable shape and size analysis
D Acevedo, ZK Nagy
Journal of crystal growth 394, 97-105, 2014
502014
Evaluation of three approaches for real-time monitoring of roller compaction with near-infrared spectroscopy
D Acevedo, A Muliadi, A Giridhar, JD Litster, RJ Romañach
Aaps Pharmscitech 13, 1005-1012, 2012
502012
Raman spectroscopy for monitoring the continuous crystallization of carbamazepine
D Acevedo, X Yang, A Mohammad, N Pavurala, WL Wu, TF O’Connor, ...
Organic Process Research & Development 22 (2), 156-165, 2018
422018
Encrustation in continuous pharmaceutical crystallization processes—a review
D Acevedo, X Yang, YC Liu, TF O’Connor, A Koswara, ZK Nagy, ...
Organic Process Research & Development 23 (6), 1134-1142, 2019
372019
Modeling and characterization of an in situ wet mill operation
D Acevedo, VK Kamaraju, B Glennon, ZK Nagy
Organic Process Research & Development 21 (7), 1069-1079, 2017
362017
Real-time feasible multi-objective optimization based nonlinear model predictive control of particle size and shape in a batch crystallization process
Y Cao, D Acevedo, ZK Nagy, CD Laird
Control Engineering Practice 69, 1-8, 2017
282017
Application of PAT-based feedback control for the crystallization of pharmaceuticals in porous media
DA Acevedo, J Ling, K Chadwick, ZK Nagy
Crystal Growth & Design, 2016
27*2016
A continuous multi-stage mixed-suspension mixed-product-removal crystallization system with fines dissolution
D Acevedo, DJ Jarmer, CL Burcham, CS Polster, ZK Nagy
Chemical Engineering Research and Design 135, 112-120, 2018
262018
Model-Based Evaluation of Direct Nucleation Control Approaches for the Continuous Cooling Crystallization of Paracetamol in a Mixed Suspension Mixed Product Removal System
D Acevedo, Y Yang, DJ Warnke, ZK Nagy
Crystal Growth & Design 17 (10), 5377-5383, 2017
252017
Evaluation of focused beam reflectance measurement (FBRM) for monitoring and predicting the crystal size of carbamazepine in crystallization processes
D Acevedo, WL Wu, X Yang, N Pavurala, A Mohammad, TF O'Connor
CrystEngComm 23 (4), 972-985, 2021
242021
Population balance model development verification and validation of cooling crystallization of carbamazepine
YC Liu, D Acevedo, X Yang, S Naimi, WL Wu, N Pavurala, ZK Nagy, ...
Crystal Growth & Design 20 (8), 5235-5250, 2020
182020
Development of a continuous synthesis process for carbamazepine using validated in-line Raman spectroscopy and kinetic modelling for disturbance simulation
M Glace, W Wu, H Kraus, D Acevedo, TD Roper, A Mohammad
Reaction Chemistry & Engineering 8 (5), 1032-1042, 2023
42023
Kinetic modelling of an environmentally friendly carbamazepine synthesis via urea and iminostilbene in batch and continuous processes
HF Kraus, D Acevedo, W Wu, TF O'Connor, A Mohammad, D Liu
Reaction Chemistry & Engineering 8 (2), 402-415, 2023
12023
Impurity Profiling for a Scalable Continuous Synthesis and Crystallization of Carbamazepine Drug Substance
M Glace, H Kraus, W Wu, D Acevedo, D Liu, TD Roper, A Mohammad
Organic Process Research & Development, 2024
2024
Development and Validation of Raman and Blaze Metrics As Process Analytical Technology (PAT) Tools to Monitor Continuous Synthesis and Crystallization of Carbamazepine
A Mohammad, M Glace, H Kraus, Y Zhang, DA Acevedo
2023 AIChE Annual Meeting, 2023
2023
Developing a Novel Size-Dependent Growth Modeling Method for the Batch Crystallization of Carbamazepine from Variable Seed Crystal Size Distributions
H Kraus, DA Acevedo, T O'Connor, D Liu, A Mohammad
2022 AIChE Annual Meeting, 2022
2022
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