| Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. A Taraboulos, M Scott, A Semenov, D Avrahami, L Laszlo, SB Prusiner, ... The Journal of cell biology 129 (1), 121-132, 1995 | 700 | 1995 |
| Single-cell transcriptomics of the human endocrine pancreas YJ Wang, J Schug, KJ Won, C Liu, A Naji, D Avrahami, ML Golson, ... Diabetes 65 (10), 3028-3038, 2016 | 378 | 2016 |
| Mutation of the prion protein in Libyan Jews with Creutzfeldt–Jakob disease K Hsiao, Z Meiner, E Kahana, C Cass, I Kahana, D Avrahami, G Scarlato, ... New England Journal of Medicine 324 (16), 1091-1097, 1991 | 336 | 1991 |
| Aging-dependent demethylation of regulatory elements correlates with chromatin state and improved β cell function D Avrahami, C Li, J Zhang, J Schug, R Avrahami, S Rao, MB Stadler, ... Cell metabolism 22 (4), 619-632, 2015 | 185 | 2015 |
| PAX6 maintains β cell identity by repressing genes of alternative islet cell types A Swisa, D Avrahami, N Eden, J Zhang, E Feleke, T Dahan, ... The Journal of clinical investigation 127 (1), 230-243, 2017 | 156 | 2017 |
| Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob disease Y Friedman-Levi, Z Meiner, T Canello, K Frid, GG Kovacs, H Budka, ... PLoS pathogens 7 (11), e1002350, 2011 | 90 | 2011 |
| Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D D Avrahami, YJ Wang, J Schug, E Feleke, L Gao, C Liu, A Naji, B Glaser, ... Molecular metabolism 42, 101057, 2020 | 73 | 2020 |
| The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells MBA Beest, SJ Chapin, D Avrahami, KE Mostov Molecular biology of the cell 16 (12), 5784-5792, 2005 | 72 | 2005 |
| Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication D Avrahami, C Li, M Yu, Y Jiao, J Zhang, A Naji, S Ziaie, B Glaser, ... The Journal of clinical investigation 124 (2), 2014 | 71 | 2014 |
| Effects of ageing and senescence on pancreatic β‐cell function A Helman, D Avrahami, A Klochendler, B Glaser, KH Kaestner, ... Diabetes, Obesity and Metabolism 18, 58-62, 2016 | 69 | 2016 |
| Universal Minicircle Sequence Binding Protein, a CCHC-type Zinc Finger Protein That Binds the Universal Minicircle Sequence of Trypanosomatids: PURIFICATION AND … Y Tzfati, H Abeliovich, D Avrahami, J Shlomai Journal of Biological Chemistry 270 (36), 21339-21345, 1995 | 59 | 1995 |
| Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication K Ou, M Yu, NG Moss, YJ Wang, AW Wang, SC Nguyen, C Jiang, ... The Journal of Clinical Investigation 129 (1), 209-214, 2019 | 54 | 2019 |
| Epigenetic regulation of pancreas development and function D Avrahami, KH Kaestner Seminars in cell & developmental biology 23 (6), 693-700, 2012 | 53 | 2012 |
| Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state XQ Dai, J Camunas-Soler, LJB Briant, T Dos Santos, AF Spigelman, ... Cell Metabolism 34 (2), 256-268. e5, 2022 | 49 | 2022 |
| Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse Y Riahi, T Israeli, R Yeroslaviz, S Chimenez, D Avrahami, ... Elife 7, e38472, 2018 | 48 | 2018 |
| Beta cell heterogeneity: an evolving concept D Avrahami, A Klochendler, Y Dor, B Glaser Diabetologia 60, 1363-1369, 2017 | 45 | 2017 |
| Induced neuroprotection independently from PrPSc accumulation in a mouse model for prion disease treated with simvastatin Y Haviv, D Avrahami, H Ovadia, T Ben-Hur, R Gabizon, R Sharon Archives of neurology 65 (6), 762-775, 2008 | 44 | 2008 |
| Examining how the MAFB transcription factor affects islet β-cell function postnatally HA Cyphert, EM Walker, Y Hang, S Dhawan, R Haliyur, L Bonatakis, ... Diabetes 68 (2), 337-348, 2019 | 35 | 2019 |
| A single-stranded DNA binding protein binds the origin of replication of the duplex kinetoplast DNA. D Avrahami, Y Tzfati, J Shlomai Proceedings of the National Academy of Sciences 92 (23), 10511-10515, 1995 | 32 | 1995 |
| Analysis of membrane traffic in polarized epithelial cells JH Lipschutz, LE O'Brien, Y Altschuler, D Avrahami, Y Nguyen, K Tang, ... Current Protocols in Cell Biology 12 (1), 15.5. 1-15.5. 18, 2001 | 31 | 2001 |
KH KaestnerDepartment of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School ofDirección de correo verificada de mail.med.upenn.edu
