James Allison
James Allison
MD Anderson Cancer Center
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Citado por
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Restoring function in exhausted CD8 T cells during chronic viral infection
DL Barber, EJ Wherry, D Masopust, B Zhu, JP Allison, AH Sharpe, ...
Nature 439 (7077), 682-687, 2006
Enhancement of antitumor immunity by CTLA-4 blockade
DR Leach, MF Krummel, JP Allison
Science 271 (5256), 1734-1736, 1996
The future of immune checkpoint therapy
P Sharma, JP Allison
Science 348 (6230), 56-61, 2015
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ...
Science 359 (6371), 97-103, 2018
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
MF Krummel, JP Allison
The Journal of experimental medicine 182 (2), 459-465, 1995
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
FA Harding, JG McArthur, JA Gross, DH Raulet, JP Allison
Nature 356 (6370), 607-609, 1992
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
BC Özdemir, T Pentcheva-Hoang, JL Carstens, X Zheng, CC Wu, ...
Cancer cell 25 (6), 719-734, 2014
Immunologic correlates of the abscopal effect in a patient with melanoma
MA Postow, MK Callahan, CA Barker, Y Yamada, J Yuan, S Kitano, Z Mu, ...
New England Journal of Medicine 366 (10), 925-931, 2012
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential
P Sharma, JP Allison
Cell 161 (2), 205-214, 2015
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
MA Curran, W Montalvo, H Yagita, JP Allison
Proceedings of the National Academy of Sciences 107 (9), 4275-4280, 2010
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
MM Gubin, X Zhang, H Schuster, E Caron, JP Ward, T Noguchi, Y Ivanova, ...
Nature 515 (7528), 577-581, 2014
Fundamental Mechanisms of Immune Checkpoint Blockade TherapyFundamental Mechanisms of Immune Checkpoint Blockade Therapy
SC Wei, CR Duffy, JP Allison
Cancer discovery 8 (9), 1069-1086, 2018
Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
SE Townsend, JP Allison
Science 259 (5093), 368-370, 1993
The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research
MA Cheever, JP Allison, AS Ferris, OJ Finn, BM Hastings, TT Hecht, ...
Clinical cancer research 15 (17), 5323-5337, 2009
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
TR Simpson, F Li, W Montalvo-Ortiz, MA Sepulveda, K Bergerhoff, F Arce, ...
Journal of Experimental Medicine 210 (9), 1695-1710, 2013
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative …
RPM Sutmuller, LM Van Duivenvoorde, A Van Elsas, TNM Schumacher, ...
The Journal of experimental medicine 194 (6), 823-832, 2001
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
H Matsushita, MD Vesely, DC Koboldt, CG Rickert, R Uppaluri, VJ Magrini, ...
Nature 482 (7385), 400-404, 2012
Combination immunotherapy of B16 melanoma using anti–cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF …
A Van Elsas, AA Hurwitz, JP Allison
The Journal of experimental medicine 190 (3), 355-366, 1999
CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy
CA Chambers, MS Kuhns, JG Egen, JP Allison
Annual review of immunology 19, 565, 2001
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