Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists K Shimono, W Tung, C Macolino, AHT Chi, JH Didizian, C Mundy, ... Nature medicine 17 (4), 454-460, 2011 | 364 | 2011 |
The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis JA Arnott, AG Lambi, C Mundy, H Hendesi, RA Pixley, TA Owen, ... Critical Reviews™ in Eukaryotic Gene Expression 21 (1), 2011 | 128 | 2011 |
The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55 H Sharir, L Console-Bram, C Mundy, SN Popoff, A Kapur, ME Abood Journal of neuroimmune pharmacology 7, 856-865, 2012 | 107 | 2012 |
Indian hedgehog roles in post-natal TMJ development and organization T Ochiai, Y Shibukawa, M Nagayama, C Mundy, T Yasuda, T Okabe, ... Journal of dental research 89 (4), 349-354, 2010 | 83 | 2010 |
Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones BM Zak, M Schuksz, E Koyama, C Mundy, DE Wells, Y Yamaguchi, ... Bone 48 (5), 979-987, 2011 | 75 | 2011 |
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses J Huegel, C Mundy, F Sgariglia, P Nygren, PC Billings, Y Yamaguchi, ... Developmental biology 377 (1), 100-112, 2013 | 74 | 2013 |
Connective tissue growth factor (CTGF/CCN2) negatively regulates BMP‐2 induced osteoblast differentiation and signaling C Mundy, M Gannon, SN Popoff Journal of cellular physiology 229 (5), 672-681, 2014 | 60 | 2014 |
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine C Mundy, T Yasuda, T Kinumatsu, Y Yamaguchi, M Iwamoto, ... Developmental biology 351 (1), 70-81, 2011 | 59 | 2011 |
Domains with highest heparan sulfate–binding affinity reside at opposite ends in BMP2/4 versus BMP5/6/7: Implications for function PC Billings, E Yang, C Mundy, M Pacifici Journal of Biological Chemistry 293 (37), 14371-14383, 2018 | 40 | 2018 |
The Skeletal site‐specific role of connective tissue growth factor in prenatal osteogenesis AG Lambi, TL Pankratz, C Mundy, M Gannon, MF Barbe, JT Richtsmeier, ... Developmental Dynamics 241 (12), 1944-1959, 2012 | 40 | 2012 |
Sulfotransferase Ndst1 is needed for mandibular and TMJ development T Yasuda, C Mundy, T Kinumatsu, Y Shibukawa, T Shibutani, K Grobe, ... Journal of dental research 89 (10), 1111-1116, 2010 | 37 | 2010 |
Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice S Sinha, C Mundy, T Bechtold, F Sgariglia, MM Ibrahim, PC Billings, ... PLoS Genetics 13 (4), e1006742, 2017 | 35 | 2017 |
Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice C Mundy, L Yao, S Sinha, J Chung, D Rux, SE Catheline, E Koyama, ... Science signaling 14 (669), eabd0536, 2021 | 25 | 2021 |
HhAntag, a hedgehog signaling antagonist, suppresses chondrogenesis and modulates canonical and non‐canonical BMP signaling C Mundy, A Bello, F Sgariglia, E Koyama, M Pacifici Journal of cellular physiology 231 (5), 1033-1044, 2016 | 22 | 2016 |
Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs TE Bechtold, C Saunders, C Mundy, H Um, RS Decker, I Salhab, N Kurio, ... Journal of dental research 95 (3), 292-301, 2016 | 21 | 2016 |
Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in hereditary multiple exostoses C Mundy, E Yang, H Takano, PC Billings, M Pacifici Journal of Biological Chemistry 293 (20), 7703-7716, 2018 | 17 | 2018 |
Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co‐Administration of a Retinoid Antagonist in Mice E Koyama, C Mundy, C Saunders, J Chung, SE Catheline, D Rux, ... Journal of Bone and Mineral Research 36 (7), 1387-1402, 2020 | 8 | 2020 |
Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function E Yang, C Mundy, EF Rappaport, M Pacifici, PC Billings PloS one 14 (9), e0222784, 2019 | 5 | 2019 |
Palovarotene Action Against Heterotopic Ossification Includes a Reduction of Local Participating Activin A‐Expressing Cell Populations C Mundy, L Yao, KA Shaughnessy, C Saunders, EM Shore, E Koyama, ... JBMR plus 7 (12), e10821, 2023 | 3 | 2023 |
Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses C Mundy, J Chung, E Koyama, S Bunting, R Mahimkar, M Pacifici Journal of Orthopaedic Research® 40 (10), 2391-2401, 2022 | 3 | 2022 |