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Reprogramming in vivo produces teratomas and iPS cells with totipotency features M Abad, L Mosteiro, C Pantoja, M Cañamero, T Rayon, I Ors, O Graña, ... Nature 502 (7471), 340-345, 2013 | 565 | 2013 |
An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms J Tapial, KCH Ha, T Sterne-Weiler, A Gohr, U Braunschweig, ... Genome research 27 (10), 1759-1768, 2017 | 346 | 2017 |
Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3 A Ragvin, E Moro, D Fredman, P Navratilova, Ø Drivenes, PG Engström, ... Proceedings of the National Academy of Sciences 107 (2), 775-780, 2010 | 239 | 2010 |
A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts E De La Calle-Mustienes, CG Feijóo, M Manzanares, JJ Tena, ... Genome research 15 (8), 1061-1072, 2005 | 238 | 2005 |
Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst T Rayon, S Menchero, A Nieto, P Xenopoulos, M Crespo, K Cockburn, ... Developmental cell 30 (4), 410-422, 2014 | 222 | 2014 |
Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head M Manzanares, H Wada, N Itasaki, PA Trainor, R Krumlauf, PWH Holland Nature 408 (6814), 854-857, 2000 | 207 | 2000 |
Genome-wide profiling of p63 DNA–binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus EN Kouwenhoven, SJ van Heeringen, JJ Tena, M Oti, BE Dutilh, ... PLoS genetics 6 (8), e1001065, 2010 | 183 | 2010 |
Segmental regulation of Hoxb-3 by kreisler M Manzanares, S Cordes, CT Kwan, MH Sham, GS Barsh, R Krumlauf Nature 387 (6629), 191-195, 1997 | 172 | 1997 |
The increasing complexity of the Snail gene superfamily in metazoan evolution M Manzanares, A Locascio, MA Nieto Trends in genetics 17 (4), 178-181, 2001 | 162 | 2001 |
Active DNA demethylation at enhancers during the vertebrate phylotypic period O Bogdanovic, AH Smits, E de la Calle Mustienes, JJ Tena, E Ford, ... Nature genetics 48 (4), 417-430, 2016 | 154 | 2016 |
Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution PA Trainor, KR Melton, M Manzanares Universidad del País Vasco, 2003 | 151 | 2003 |
Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family M Maconochie, R Krishnamurthy, S Nonchev, P Meier, M Manzanares, ... Development 126 (7), 1483-1494, 1999 | 150 | 1999 |
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation. S Nonchev, M Maconochie, C Vesque, S Aparicio, L Ariza-McNaughton, ... Proceedings of the National Academy of Sciences 93 (18), 9339-9345, 1996 | 133 | 1996 |
Conserved and distinct roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 genes M Manzanares, S Cordes, L Ariza-McNaughton, V Sadl, K Maruthainar, ... Development 126 (4), 759-769, 1999 | 132 | 1999 |
Active DNA demethylation at enhancers during the vertebrate phylotypic period O Bogdanović, AH Smits, E de la Calle Mustienes, JJ Tena, E Ford, ... Nature genetics 48 (4), 417-426, 2016 | 131 | 2016 |
Modularity and reshuffling of Snail and Slug expression during vertebrate evolution A Locascio, M Manzanares, MJ Blanco, MA Nieto Proceedings of the National Academy of Sciences 99 (26), 16841-16846, 2002 | 130 | 2002 |
Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms M Manzanares, S Bel-Vialar, L Ariza-McNaughton, E Ferretti, H Marshall, ... Oxford University Press for The Company of Biologists Limited 128 (18), 3595 …, 2001 | 128 | 2001 |
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes D Martin, C Pantoja, AF Miñán, C Valdes-Quezada, E Moltó, F Matesanz, ... Nature structural & molecular biology 18 (6), 708-714, 2011 | 126 | 2011 |
The Role of kreisler in Segmentation during Hindbrain Development M Manzanares, PA Trainor, S Nonchev, L Ariza-McNaughton, J Brodie, ... Developmental biology 211 (2), 220-237, 1999 | 109 | 1999 |