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Alexander G Fletcher
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Vertex models of epithelial morphogenesis
AG Fletcher, M Osterfield, RE Baker, SY Shvartsman
Biophysical journal 106 (11), 2291-2304, 2014
6392014
Chaste: an open source C++ library for computational physiology and biology
GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ...
PLoS computational biology 9 (3), e1002970, 2013
5192013
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
3092009
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon
AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ...
Cell reports 8 (4), 940-947, 2014
2382014
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
JM Osborne, AG Fletcher, JM Pitt-Francis, PK Maini, DJ Gavaghan
PLoS computational biology 13 (2), e1005387, 2017
2332017
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
1872009
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework
AG Fletcher, JM Osborne, PK Maini, DJ Gavaghan
Progress in biophysics and molecular biology 113 (2), 299-326, 2013
1822013
Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance
D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ...
PLoS computational biology 11 (9), e1004493, 2015
1752015
A hybrid approach to multi-scale modelling of cancer
JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010
1552010
Mechanisms and mechanics of cell competition in epithelia
JP Vincent, AG Fletcher, LAL Baena-Lopez
Nature reviews Molecular cell biology 14 (9), 581-591, 2013
1512013
A PHABULOSA/cytokinin feedback loop controls root growth in Arabidopsis
RD Ioio, C Galinha, AG Fletcher, SP Grigg, A Molnar, V Willemsen, ...
Current Biology 22 (18), 1699-1704, 2012
1482012
A computational study of discrete mechanical tissue models
P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ...
Physical biology 6 (3), 036001, 2009
1482009
Migration and horizontal gene transfer divide microbial genomes into multiple niches
R Niehus, S Mitri, AG Fletcher, KR Foster
Nature communications 6 (1), 8924, 2015
1442015
Mechanocellular models of epithelial morphogenesis
AG Fletcher, F Cooper, RE Baker
Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017
1142017
Unipolar distributions of junctional Myosin II identify cell stripe boundaries that drive cell intercalation throughout Drosophila axis extension
RJ Tetley, GB Blanchard, AG Fletcher, RJ Adams, B Sanson
Elife 5, e12094, 2016
1132016
Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi
A Parker, OJ Maclaren, AG Fletcher, D Muraro, PA Kreuzaler, HM Byrne, ...
The FASEB Journal 31 (2), 636, 2017
1012017
Oxygen consumption dynamics in steady-state tumour models
DR Grimes, AG Fletcher, M Partridge
Royal Society open science 1 (1), 140080, 2014
862014
Morphological plant modeling: unleashing geometric and topological potential within the plant sciences
A Bucksch, A Atta-Boateng, AF Azihou, D Battogtokh, A Baumgartner, ...
Frontiers in plant science 8, 900, 2017
852017
Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation
A Parker, L Vaux, AM Patterson, A Modasia, D Muraro, AG Fletcher, ...
Cell death & disease 10 (2), 108, 2019
832019
Mathematical modeling of monoclonal conversion in the colonic crypt
AG Fletcher, CJW Breward, SJ Chapman
Journal of theoretical biology 300, 118-133, 2012
792012
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Articles 1–20