Chemistry of the retinoid (visual) cycle PD Kiser, M Golczak, K Palczewski Chemical reviews 114 (1), 194-232, 2014 | 334 | 2014 |
Key enzymes of the retinoid (visual) cycle in vertebrate retina PD Kiser, M Golczak, A Maeda, K Palczewski Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 193 | 2012 |
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle PD Kiser, M Golczak, DT Lodowski, MR Chance, K Palczewski Proceedings of the National Academy of Sciences 106 (41), 17325-17330, 2009 | 161 | 2009 |
The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision J von Lintig, PD Kiser, M Golczak, K Palczewski Trends in biochemical sciences 35 (7), 400-410, 2010 | 131 | 2010 |
Structural basis of carotenoid cleavage: from bacteria to mammals X Sui, PD Kiser, J von Lintig, K Palczewski Archives of biochemistry and biophysics 539 (2), 203-213, 2013 | 129 | 2013 |
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina M Golczak, A Maeda, G Bereta, T Maeda, PD Kiser, S Hunzelmann, ... Journal of Biological Chemistry 283 (15), 9543-9554, 2008 | 104 | 2008 |
Retinoids and retinal diseases PD Kiser, K Palczewski Annual review of vision science 2, 197-234, 2016 | 87 | 2016 |
Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor S Gulati, H Jin, I Masuho, T Orban, Y Cai, E Pardon, KA Martemyanov, ... Nature communications 9 (1), 1996, 2018 | 81 | 2018 |
Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing S Suh, EH Choi, H Leinonen, AT Foik, GA Newby, WH Yeh, Z Dong, ... Nature biomedical engineering 5 (2), 169-178, 2021 | 80 | 2021 |
Structural basis for the acyltransferase activity of lecithin: retinol acyltransferase-like proteins M Golczak, PD Kiser, AE Sears, DT Lodowski, WS Blaner, K Palczewski Journal of Biological Chemistry 287 (28), 23790-23807, 2012 | 78 | 2012 |
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision PD Kiser, J Zhang, M Badiee, Q Li, W Shi, X Sui, M Golczak, GP Tochtrop, ... Nature chemical biology 11 (6), 409-415, 2015 | 77 | 2015 |
Membrane-binding and enzymatic properties of RPE65 PD Kiser, K Palczewski Progress in retinal and eye research 29 (5), 428-442, 2010 | 76 | 2010 |
Molecular pharmacodynamics of emixustat in protection against retinal degeneration J Zhang, PD Kiser, M Badiee, G Palczewska, Z Dong, M Golczak, ... The Journal of clinical investigation 125 (7), 2781-2794, 2015 | 74 | 2015 |
Characterization of the role of β-carotene 9, 10-dioxygenase in macular pigment metabolism D Babino, G Palczewski, MAK Widjaja-Adhi, PD Kiser, M Golczak, ... Journal of Biological Chemistry 290 (41), 24844-24857, 2015 | 72 | 2015 |
Importance of membrane structural integrity for RPE65 retinoid isomerization activity M Golczak, PD Kiser, DT Lodowski, A Maeda, K Palczewski Journal of biological chemistry 285 (13), 9667-9682, 2010 | 71 | 2010 |
Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis PD Kiser, ER Farquhar, W Shi, X Sui, MR Chance, K Palczewski Proceedings of the National Academy of Sciences 109 (41), E2747-E2756, 2012 | 63 | 2012 |
Shedding new light on the generation of the visual chromophore K Palczewski, PD Kiser Proceedings of the National Academy of Sciences 117 (33), 19629-19638, 2020 | 48 | 2020 |
Utilization of Dioxygen by Carotenoid Cleavage Oxygenases*♦ X Sui, M Golczak, J Zhang, KA Kleinberg, J von Lintig, K Palczewski, ... Journal of Biological Chemistry 290 (51), 30212-30223, 2015 | 48 | 2015 |
LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3 M Golczak, AE Sears, PD Kiser, K Palczewski Nature chemical biology 11 (1), 26-32, 2015 | 48 | 2015 |
The biochemical basis of vitamin A production from the asymmetric carotenoid β-cryptoxanthin ME Kelly, S Ramkumar, W Sun, C Colon Ortiz, PD Kiser, M Golczak, ... ACS chemical biology 13 (8), 2121-2129, 2018 | 45 | 2018 |