| Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration S Felszeghy, J Viiri, JJ Paterno, JMT Hyttinen, A Koskela, M Chen, ... Redox biology 20, 1-12, 2019 | 123 | 2019 |
| Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing S Suh, EH Choi, H Leinonen, AT Foik, GA Newby, WH Yeh, Z Dong, ... Nature biomedical engineering 5 (2), 169-178, 2021 | 99 | 2021 |
| Vision in laboratory rodents—Tools to measure it and implications for behavioral research H Leinonen, H Tanila Behavioural brain research 352, 172-182, 2018 | 71 | 2018 |
| Retinal degeneration in a mouse model of CLN5 disease is associated with compromised autophagy H Leinonen, V Keksa-Goldsteine, S Ragauskas, P Kohlmann, Y Singh, ... Scientific reports 7 (1), 1597, 2017 | 63 | 2017 |
| Retinoids in the visual cycle: role of the retinal G protein-coupled receptor EH Choi, A Daruwalla, S Suh, H Leinonen, K Palczewski Journal of lipid research 62, 2021 | 49 | 2021 |
| Early retinal function deficit without prominent morphological changes in the R6/2 mouse model of Huntington’s disease S Ragauskas, H Leinonen, J Puranen, S Rönkkö, S Nymark, K Gurevicius, ... PLoS One 9 (12), e113317, 2014 | 45 | 2014 |
| Anti‐inflammatory effects of ADAMTS‐4 in a mouse model of ischemic stroke S Lemarchant, H Dunghana, Y Pomeshchik, H Leinonen, N Kolosowska, ... Glia 64 (9), 1492-1507, 2016 | 44 | 2016 |
| In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration EH Choi, S Suh, AT Foik, H Leinonen, GA Newby, XD Gao, S Banskota, ... Nature communications 13 (1), 1830, 2022 | 43 | 2022 |
| Photic generation of 11-cis-retinal in bovine retinal pigment epithelium J Zhang, EH Choi, A Tworak, D Salom, H Leinonen, CL Sander, ... Journal of Biological Chemistry 294 (50), 19137-19154, 2019 | 39 | 2019 |
| Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease H Leinonen, NC Pham, T Boyd, J Santoso, K Palczewski, F Vinberg Elife 9, e59422, 2020 | 38 | 2020 |
| Chronic pyruvate supplementation increases exploratory activity and brain energy reserves in young and middle-aged mice H Koivisto, H Leinonen, M Puurula, HS Hafez, GA Barrera, MH Stridh, ... Frontiers in Aging Neuroscience 8, 41, 2016 | 34 | 2016 |
| Normal amplitude of electroretinography and visual evoked potential responses in AβPP/PS1 mice H Leinonen, A Lipponen, K Gurevicius, H Tanila Journal of Alzheimer's Disease 51 (1), 21-26, 2016 | 26 | 2016 |
| Lack of P4H-TM in mice results in age-related retinal and renal alterations H Leinonen, M Rossi, AM Salo, P Tiainen, J Hyvärinen, M Pitkänen, ... Human Molecular Genetics 25 (17), 3810-3823, 2016 | 23 | 2016 |
| A p97/valosin-containing protein inhibitor drug CB-5083 has a potent but reversible off-target effect on phosphodiesterase-6 H Leinonen, C Cheng, M Pitkänen, CL Sander, J Zhang, S Saeid, ... Journal of Pharmacology and Experimental Therapeutics 378 (1), 31-41, 2021 | 20 | 2021 |
| A Combination of G Protein–Coupled Receptor Modulators Protects Photoreceptors from Degeneration T Orban, H Leinonen, T Getter, Z Dong, W Sun, S Gao, A Veenstra, ... Journal of Pharmacology and Experimental Therapeutics 364 (2), 207-220, 2018 | 19 | 2018 |
| Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice H Leinonen, H Koivisto, HR Lipponen, A Matilainen, AM Salo, EY Dimova, ... Neuropharmacology 153, 63-72, 2019 | 17 | 2019 |
| Inhibition of ceramide accumulation in AdipoR1–/–mice increases photoreceptor survival and improves vision D Lewandowski, AT Foik, R Smidak, EH Choi, J Zhang, T Hoang, ... JCI insight 7 (4), 2022 | 12 | 2022 |
| An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease EH Choi, S Suh, DE Einstein, H Leinonen, Z Dong, SR Rao, SJ Fliesler, ... JCI insight 6 (9), 2021 | 12 | 2021 |
| A mixture of US food and drug administration–approved monoaminergic drugs protects the retina from light damage in diverse models of night blindness H Leinonen, EH Choi, A Gardella, VJ Kefalov, K Palczewski Investigative Ophthalmology & Visual Science 60 (5), 1442-1453, 2019 | 12 | 2019 |
| Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice Y Singh, H Leinonen, F Fazaludeen, M Jaronen, D Guest, N Buckley, ... Human Molecular Genetics 28 (19), 3309-3322, 2019 | 11 | 2019 |
