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Gal Ofir
Gal Ofir
Max Planck Institute for Biology Tübingen
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Systematic discovery of antiphage defense systems in the microbial pangenome
S Doron, S Melamed, G Ofir, A Leavitt, A Lopatina, M Keren, G Amitai, ...
Science 359 (6379), eaar4120, 2018
8672018
BREX is a novel phage resistance system widespread in microbial genomes
T Goldfarb, H Sberro, E Weinstock, O Cohen, S Doron, ...
The EMBO journal 34 (2), 169-183, 2015
4842015
DISARM is a widespread bacterial defence system with broad anti-phage activities
G Ofir, S Melamed, H Sberro, Z Mukamel, S Silverman, G Yaakov, ...
Nature microbiology 3 (1), 90, 2018
2832018
STING cyclic dinucleotide sensing originated in bacteria
BR Morehouse, AA Govande, A Millman, AFA Keszei, B Lowey, G Ofir, ...
Nature 586 (7829), 429-433, 2020
2702020
Contemporary Phage Biology: From Classic Models to New Insights
G Ofir, R Sorek
Cell 172 (6), 1260-1270, 2018
2602018
Antiviral activity of bacterial TIR domains via immune signalling molecules
G Ofir, E Herbst, M Baroz, D Cohen, A Millman, S Doron, N Tal, ...
Nature 600 (7887), 116-120, 2021
1962021
Prokaryotic viperins produce diverse antiviral molecules
A Bernheim, A Millman, G Ofir, G Meitav, C Avraham, H Shomar, ...
Nature 589 (7840), 120-124, 2021
1872021
An expanded arsenal of immune systems that protect bacteria from phages
A Millman, S Melamed, A Leavitt, S Doron, A Bernheim, J Hör, J Garb, ...
Cell Host & Microbe, 2022
1722022
Systematic discovery of antiphage defense systems in the microbial pangenome. Science 359: eaar4120
S Doron, S Melamed, G Ofir, A Leavitt, A Lopatina, M Keren, G Amitai, ...
692018
Conservation of antiviral systems across domains of life reveals novel immune mechanisms in humans
J Cury, E Mordret, V Hernandez-Trejo, F Tesson, G Ofir, EZ Poirier, ...
bioRxiv, 2022.12. 12.520048, 2022
162022
Vesicles Spread Susceptibility to Phages
G Ofir, R Sorek
Cell 168 (1-2), 13-15, 2017
122017
Class I DISARM provides anti-phage and anti-conjugation activity by unmethylated DNA recognition
C Aparicio-Maldonado, G Ofir, A Salini, R Sorek, FL Nobrega, SJJ Brouns
bioRxiv, 2021.12. 28.474362, 2021
62021
The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
J Garb, G Amitai, A Lu, G Ofir, A Brandis, T Mehlman, PJ Kranzusch, ...
PloS one 19 (4), e0302251, 2024
42024
Activation of Thoeris antiviral system via SIR2 effector filament assembly
G Tamulaitiene, D Sabonis, G Sasnauskas, A Ruksenaite, A Silanskas, ...
Nature, 1-6, 2024
32024
Antiviral activity of bacterial TIR domains via signaling molecules that trigger cell death
G Ofir, E Herbst, M Baroz, D Cohen, A Millman, S Doron, N Tal, ...
bioRxiv, 2021
2*2021
An expanding arsenal of immune systems that protect bacteria from phages
A Millman, S Melamed, A Leavitt, S Doron, A Bernheim, J Hör, A Lopatina, ...
bioRxiv, 2022
2022
Genetic systems that defend against foreign dna and uses thereof
R Sorek, G Ofir, G Amitai, S Melamed, S Doron, A Leavitt
US Patent App. 16/614,370, 2020
2020
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