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Joshua W. Modell
Joshua W. Modell
Assistant Professor of Molecular Biology & Genetics, Johns Hopkins School of Medicine
Verified email at jhmi.edu - Homepage
Title
Cited by
Cited by
Year
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ...
science 313 (5795), 1929-1935, 2006
51832006
Cas9 specifies functional viral targets during CRISPR–Cas adaptation
R Heler, P Samai, JW Modell, C Weiner, GW Goldberg, D Bikard, ...
Nature 519 (7542), 199-202, 2015
5322015
CRISPR–Cas systems exploit viral DNA injection to establish and maintain adaptive immunity
JW Modell, W Jiang, LA Marraffini
Nature 544 (7648), 101-104, 2017
1542017
A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW
JW Modell, AC Hopkins, MT Laub
Genes & development 25 (12), 1328-1343, 2011
1402011
A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus
JW Modell, TK Kambara, BS Perchuk, MT Laub
PLoS biology 12 (10), e1001977, 2014
1142014
Chordin is required for neural but not axial development in sea urchin embryos
CA Bradham, C Oikonomou, A Kühn, AB Core, JW Modell, DR McClay, ...
Developmental biology 328 (2), 221-233, 2009
732009
A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression
RE Workman, T Pammi, BTK Nguyen, LW Graeff, E Smith, SM Sebald, ...
Cell 184 (3), 675-688. e19, 2021
522021
Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts
GW Goldberg, EA McMillan, A Varble, JW Modell, P Samai, W Jiang, ...
Nature communications 9 (1), 61, 2018
412018
Cleavage of viral DNA by restriction endonucleases stimulates the type II CRISPR-Cas immune response
P Maguin, A Varble, JW Modell, LA Marraffini
Molecular cell 82 (5), 907-919. e7, 2022
292022
Viral recombination systems limit CRISPR-Cas targeting through the generation of escape mutations
AA Hossain, J McGinn, AJ Meeske, JW Modell, LA Marraffini
Cell host & microbe 29 (10), 1482-1495. e12, 2021
152021
Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase
K Gozzi, NT Tran, JW Modell, TBK Le, MT Laub
PLoS biology 20 (11), e3001790, 2022
112022
Mitochondrial gradients and p38 activity in early sea urchin embryos
JW Modell, CA Bradham
Molecular reproduction and development 78 (4), 225-225, 2011
52011
Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense
RE Workman, MJ Stoltzfus, NC Keith, CW Euler, J Bondy-Denomy, ...
Cell Reports 43 (3), 2024
22024
A DNA Damage-Induced
JW Modell, TK Kambara, BS Perchuk, MT Laub
SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus …, 2014
22014
about cmap
J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ...
Science 313, 1929-1935, 2006
22006
A dynamic subpopulation of CRISPR-Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage
MJ Stoltzfus, RE Workman, NC Keith, JW Modell
bioRxiv, 2024.01. 11.575229, 2024
2024
Regulatory pathways controlling cell division after DNA damage in Caulobacter crescentus
JW Modell
Massachusetts Institute of Technology, 2013
2013
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