Seguir
Nicholas Denko
Nicholas Denko
professor of radiation oncology ohio state uiversity
Dirección de correo verificada de osumc.edu
Título
Citado por
Citado por
Año
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou, RA Cairns, L Fontana, AL Lim, NC Denko
Cell metabolism 3 (3), 187-197, 2006
23412006
Hypoxia, HIF1 and glucose metabolism in the solid tumour
NC Denko
Nature Reviews Cancer 8 (9), 705-713, 2008
17592008
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ...
Cancer research 64 (17), 5943-5947, 2004
6512004
FoxO3 regulates neural stem cell homeostasis
VM Renault, VA Rafalski, AA Morgan, DAM Salih, JO Brett, AE Webb, ...
Cell stem cell 5 (5), 527-539, 2009
5762009
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
I Papandreou, NC Denko, M Olson, H Van Melckebeke, S Lust, A Tam, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1311-1314, 2011
4952011
Candidate genes for the hypoxic tumor phenotype
AC Koong, NC Denko, KM Hudson, C Schindler, L Swiersz, C Koch, ...
Cancer research 60 (4), 883-887, 2000
4302000
Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment
R Cairns, I Papandreou, N Denko
Molecular Cancer Research 4 (2), 61-70, 2006
3992006
Investigating hypoxic tumor physiology through gene expression patterns
NC Denko, LA Fontana, KM Hudson, PD Sutphin, S Raychaudhuri, ...
Oncogene 22 (37), 5907-5914, 2003
3832003
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
I Papandreou, AL Lim, K Laderoute, NC Denko
Cell Death & Differentiation 15 (10), 1572-1581, 2008
3812008
Hypoxia links ATR and p53 through replication arrest
EM Hammond, NC Denko, MJ Dorie, RT Abraham, AJ Giaccia
Molecular and cellular biology 22 (6), 1834-1843, 2002
3782002
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α
DA Chan, PD Sutphin, NC Denko, AJ Giaccia
Journal of biological chemistry 277 (42), 40112-40117, 2002
3372002
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1α
DA Chan, PD Sutphin, NC Denko, AJ Giaccia
Journal of biological chemistry 277 (42), 40112-40117, 2002
3372002
Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth
RC Sun, NC Denko
Cell metabolism 19 (2), 285-292, 2014
3002014
Hypoxic gene expression and metastasis
QT Le, NC Denko, AJ Giaccia
Cancer and Metastasis Reviews 23, 293-310, 2004
2862004
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
AB Johnson, N Denko, MC Barton
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 640 (1 …, 2008
2832008
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.
NC Denko, AJ Giaccia, JR Stringer, PJ Stambrook
Proceedings of the National Academy of Sciences 91 (11), 5124-5128, 1994
2701994
Hypoxic Activation of Nuclear Factor-κB Is Mediated by a Ras and Raf Signaling Pathway and Does Not Involve MAP Kinase (ERK1 or ERK2)
AC Koong, EY Chen, NF Mivechi, NC Denko, P Stambrook, AJ Giaccia
Cancer Research 54 (20), 5273-5279, 1994
2041994
Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
Y Chen, R Cairns, I Papandreou, A Koong, NC Denko
PloS one 4 (9), e7033, 2009
2032009
Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
Y Chen, R Cairns, I Papandreou, A Koong, NC Denko
PloS one 4 (9), e7033, 2009
2032009
Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy
RA Cairns, I Papandreou, PD Sutphin, NC Denko
Proceedings of the National Academy of Sciences 104 (22), 9445-9450, 2007
1992007
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20