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Matthew P Hanley
Matthew P Hanley
Loxo Oncology at Lilly
Verified email at loxooncology.com
Title
Cited by
Cited by
Year
Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia
MP Hanley, MA Hahn, AX Li, X Wu, J Lin, J Wang, AH Choi, Z Ouyang, ...
Oncogene 36 (35), 5035-5044, 2017
832017
FP14. 07 combination osimertinib plus selpercatinib for EGFR-mutant non-small cell lung cancer (NSCLC) with acquired RET fusions
J Rotow, J Patel, M Hanley, H Yu, J Goldman, H Nechustan, M Scheffler, ...
Journal of Thoracic Oncology 16 (3), S230, 2021
272021
Dietary methyl donor depletion suppresses intestinal adenoma development
MP Hanley, K Kadaveru, C Perret, C Giardina, DW Rosenberg
Cancer Prevention Research 9 (10), 812-820, 2016
242016
One-carbon metabolism and colorectal cancer: Potential mechanisms of chemoprevention
MP Hanley, DW Rosenberg
Current pharmacology reports 1, 197-205, 2015
232015
A phase I study of LY3410738, a first-in-class covalent inhibitor of mutant IDH1 in cholangiocarcinoma and other advanced solid tumors.
JM Pauff, KP Papadopoulos, F Janku, AA Turk, L Goyal, RT Shroff, ...
Journal of Clinical Oncology 39 (3_suppl), TPS350-TPS350, 2021
172021
An immunotherapeutic CD137 agonist releases eomesodermin from ThPOK repression in CD4 T cells
P Mittal, R Abblett, JM Ryan, AT Hagymasi, A Agyekum-Yamoah, ...
The Journal of Immunology 200 (4), 1513-1526, 2018
102018
Osimertinib and Selpercatinib Efficacy, Safety, and Resistance in a Multicenter, Prospectively Treated Cohort of EGFR-Mutant and RET Fusion-Positive Lung …
J Rotow, JD Patel, MP Hanley, H Yu, M Awad, JW Goldman, ...
Clinical Cancer Research 29 (16), 2979-2987, 2023
92023
Methyl donor deficiency blocks colorectal cancer development by affecting key metabolic pathways
MP Hanley, O Aladelokun, K Kadaveru, DW Rosenberg
Cancer Prevention Research 13 (1), 1-14, 2020
92020
Associations of dietary fat with risk of early neoplasia in the proximal colon in a population-based case–control study
A Mo, R Wu, JP Grady, MP Hanley, M Toro, H Swede, TJ Devers, ...
Cancer Causes & Control 29, 667-674, 2018
92018
Fatty acid metabolism and colon cancer protection by dietary methyl donor restriction
O Aladelokun, M Hanley, J Mu, JC Giardina, DW Rosenberg, C Giardina
Metabolomics 17, 1-11, 2021
82021
A novel bioactive derivative of eicosapentaenoic acid (EPA) suppresses intestinal tumor development in ApcΔ14/+ mice
M Nakanishi, MP Hanley, R Zha, Y Igarashi, MA Hull, G Mathias, ...
Carcinogenesis 39 (3), 429-438, 2018
62018
Abstract OT3-08-01: a phase 1 trial of LOXO-783, a potent, highly mutant-selective, brain-penetrant allosteric PI3Kα H1047R inhibitor in PIK3CA H1047R-mutant advanced breast …
D Juric, K Jhaveri, M Beeram, E Hamilton, V Chau, MP Hanley, S Liu, ...
Cancer Research 83 (5_Supplement), OT3-08-01-OT3-08-01, 2023
12023
A Novel Derivative of Eicosapentaenoic Acid Reduces Intestinal Tumor Burden in the APCÎ" 14/+ Mouse Model of Familial Adenomatous Polyposis
M Nakanishi, MP Hanley, G Mathias, F Sciavolino, M Hull, DW Rosenberg
Gastroenterology 152 (5), S142, 2017
12017
Metabolomic profiling of APCΔ14/+ mice maintained on a methyl donor deficient diet reveals alterations to methionine and fatty acid metabolism associated with …
MP Hanley, DW Rosenberg
Cancer Research 75 (15_Supplement), 893-893, 2015
12015
Proximal human aberrant crypt foci as surrogate markers of colorectal cancer risk
DA Drew, MP Hanley, A Mo, G Goh, NA Horelik, TJ Devers, J Levine, ...
Cancer Research 74 (19_Supplement), 3240-3240, 2014
12014
Dietary Methyl Donor Restriction Alters Lipid Metabolism in a Colorectal Cancer Model
O Aladelokun, M Hanley, T Moore, J Mu, C Giardina, D Rosenberg
INTERNATIONAL JOURNAL OF TOXICOLOGY 40 (1), 70-70, 2021
2021
A NOVEL SALT OF RESOLVIN E1 CONTROLS DISEASE ACTIVITY IN THE DEXTRAN SULFATE SODIUM COLITIS MOUSE MODEL AND REDUCES INFLAMMATION IN COLON TISSUE EXPLANTS FROM ULCERATIVE …
MP Hanley, F Sciavolino, M Murray, A Mittal, M Nakanishi, G Mathias, ...
Digestive Disease Week (DDW) Conference Location San Diego, CA, S617-S618, 2019
2019
Cancer protection associated with dietary methyl donor deficiency is characterized by persistent changes to epithelial proliferation and metabolism
MP Hanley, DW Rosenberg
Cancer Research 76 (14_Supplement), 899-899, 2016
2016
The Role of One-Carbon Metabolism in the Development and Prevention of Colorectal Cancer
MP Hanley
2016
Gene expression profiling identifies Sulindac-resistant colon tumors
MP Hanley, S Miyamoto, D Rosenberg
Cancer Research 74 (19_Supplement), 237-237, 2014
2014
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