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Luca Magnani
Luca Magnani
Breast Epigenetic Plasticity and Evolution Lab, Institute of Cancer Research
Dirección de correo verificada de icr.ac.uk - Página principal
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Poised epigenetic states and acquired drug resistance in cancer
R Brown, E Curry, L Magnani, CS Wilhelm-Benartzi, J Borley
Nature Reviews Cancer 14 (11), 747-753, 2014
3152014
PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer
L Magnani, EB Ballantyne, X Zhang, M Lupien
PLoS genetics 7 (11), e1002368, 2011
2192011
Pioneer factors: directing transcriptional regulators within the chromatin environment
L Magnani, J Eeckhoute, M Lupien
Trends in Genetics 27 (11), 465-474, 2011
1942011
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer
L Magnani, A Stoeck, X Zhang, A Lánczky, AC Mirabella, TL Wang, ...
Proceedings of the National Academy of Sciences 110 (16), E1490-E1499, 2013
1882013
Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer
A Harrod, J Fulton, VTM Nguyen, M Periyasamy, L Ramos-Garcia, CF Lai, ...
Oncogene 36 (16), 2286-2296, 2017
1762017
Guidelines for the selection of functional assays to evaluate the hallmarks of cancer
O Menyhárt, H Harami-Papp, S Sukumar, R Schäfer, L Magnani, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866 (2), 300-319, 2016
1612016
Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts
N Ferrari, R Ranftl, I Chicherova, ND Slaven, E Moeendarbary, ...
Nature communications 10 (1), 130, 2019
1342019
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion
VTM Nguyen, I Barozzi, M Faronato, Y Lombardo, JH Steel, N Patel, ...
Nature communications 6 (1), 10044, 2015
1342015
APOBEC3B-mediated cytidine deamination is required for estrogen receptor action in breast cancer
M Periyasamy, H Patel, CF Lai, VTM Nguyen, E Nevedomskaya, A Harrod, ...
Cell reports 13 (1), 108-121, 2015
1272015
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
E Mensà, M Guescini, A Giuliani, MG Bacalini, D Ramini, G Corleone, ...
Journal of extracellular vesicles 9 (1), 1725285, 2020
1232020
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer
DK Patten, G Corleone, B Győrffy, Y Perone, N Slaven, I Barozzi, E Erdős, ...
Nature Medicine 24 (9), 1469-1480, 2018
1202018
FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression
V Varghese, L Magnani, N Harada-Shoji, F Mauri, RM Szydlo, S Yao, ...
Scientific reports 9 (1), 1505, 2019
1162019
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, ...
Nature communications 9 (1), 1845, 2018
1122018
Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy
SP Hong, TE Chan, Y Lombardo, G Corleone, N Rotmensz, S Bravaccini, ...
Nature communications 10 (1), 3840, 2019
1112019
Spearhead nanometric field-effect transistor sensors for single-cell analysis
Y Zhang, J Clausmeyer, B Babakinejad, A López Córdoba, T Ali, ...
Acs Nano 10 (3), 3214-3221, 2016
1002016
Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer
L Magnani, G Frige, RM Gadaleta, G Corleone, S Fabris, H Kempe, ...
Nature genetics 49 (3), 444-450, 2017
992017
Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells
Y Lombardo, M Faronato, A Filipovic, V Vircillo, L Magnani, RC Coombes
Breast cancer research 16, 1-14, 2014
942014
Expression of CDK7, cyclin H, and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor–positive breast cancer
H Patel, R Abduljabbar, CF Lai, M Periyasamy, A Harrod, C Gemma, ...
Clinical Cancer Research 22 (23), 5929-5938, 2016
922016
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
Nature communications 11 (1), 1923, 2020
902020
Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts
K Wang, S Sengupta, L Magnani, CA Wilson, RW Henry, JG Knott
PloS one 5 (5), e10622, 2010
792010
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Artículos 1–20