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William Allen
William Allen
Senior Research Associate, University of Bristol
Dirección de correo verificada de bristol.ac.uk
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Crystal structure of the FimD usher bound to its cognate FimC–FimH substrate
G Phan, H Remaut, T Wang, WJ Allen, KF Pirker, A Lebedev, ...
Nature 474 (7349), 49-53, 2011
2152011
Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG–SecDF–YajC–YidC
RJ Schulze, J Komar, M Botte, WJ Allen, S Whitehouse, VAM Gold, ...
Proceedings of the National Academy of Sciences 111 (13), 4844-4849, 2014
1652014
Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
WJ Allen, RA Corey, P Oatley, RB Sessions, SA Baldwin, SE Radford, ...
Elife 5, e15598, 2016
1202016
Pilus biogenesis at the outer membrane of Gram-negative bacterial pathogens
WJ Allen, G Phan, G Waksman
Current opinion in structural biology 22 (4), 500-506, 2012
932012
Channel crossing: how are proteins shipped across the bacterial plasma membrane?
I Collinson, RA Corey, WJ Allen
Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015
832015
Specific cardiolipin–SecY interactions are required for proton-motive force stimulation of protein secretion
RA Corey, E Pyle, WJ Allen, DW Watkins, M Casiraghi, B Miroux, ...
Proceedings of the National Academy of Sciences 115 (31), 7967-7972, 2018
732018
Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex
S Whitehouse, VAM Gold, A Robson, WJ Allen, RB Sessions, I Collinson
Journal of Cell Biology 199 (6), 919-929, 2012
642012
Dynamic action of the Sec machinery during initiation, protein translocation and termination
T Fessl, D Watkins, P Oatley, WJ Allen, RA Corey, J Horne, SA Baldwin, ...
Elife 7, e35112, 2018
612018
A high-resolution luminescent assay for rapid and continuous monitoring of protein translocation across biological membranes
GC Pereira, WJ Allen, DW Watkins, L Buddrus, D Noone, X Liu, ...
Journal of molecular biology 431 (8), 1689-1699, 2019
482019
Unlocking the bacterial SecY translocon
RA Corey, WJ Allen, J Komar, S Masiulis, S Menzies, A Robson, ...
Structure 24 (4), 518-527, 2016
452016
Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis
S Alvira, DW Watkins, L Troman, WJ Allen, JS Lorriman, G Degliesposti, ...
Elife 9, e60669, 2020
412020
ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery
RA Corey, Z Ahdash, A Shah, E Pyle, WJ Allen, T Fessl, JE Lovett, ...
Elife 8, e41803, 2019
392019
dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the “nucleotide-binding” state
PJ Rothwell, WJ Allen, E Sisamakis, S Kalinin, S Felekyan, J Widengren, ...
Journal of Biological Chemistry 288 (19), 13575-13591, 2013
332013
An intramolecular FRET system monitors fingers subdomain opening in Klentaq1
WJ Allen, PJ Rothwell, G Waksman
Protein Science 17 (3), 401-408, 2008
302008
Refined measurement of SecA-driven protein secretion reveals that translocation is indirectly coupled to ATP turnover
WJ Allen, DW Watkins, MS Dillingham, I Collinson
Proceedings of the National Academy of Sciences 117 (50), 31808-31816, 2020
272020
Dissection of pilus tip assembly by the FimD usher monomer
WJ Allen, G Phan, SJ Hultgren, G Waksman
Journal of molecular biology 425 (5), 958-967, 2013
232013
Structural biology of periplasmic chaperones
WJ Allen, G Phan, G Waksman
Advances in protein chemistry and structural biology 78, 51-97, 2009
222009
Genetic Evidence for SecY Translocon-Mediated Import of Two Contact-Dependent Growth Inhibition (CDI) Toxins
AM Jones, P Virtanen, D Hammarlöf, WJ Allen, I Collinson, CS Hayes, ...
Mbio 12 (1), e03367-20, 2021
212021
HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon
Z Ahdash, E Pyle, WJ Allen, RA Corey, I Collinson, A Politis
Elife 8, e47402, 2019
212019
Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes
HC Ford, WJ Allen, GC Pereira, X Liu, MS Dillingham, I Collinson
elife 11, e75426, 2022
202022
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