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Frank LaFerla
Frank LaFerla
Dirección de correo verificada de uci.edu
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Año
Alzheimer's disease
HW Querfurth, FM LaFerla
New England Journal of Medicine 362 (4), 329-344, 2010
57482010
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction
S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ...
Neuron 39 (3), 409-421, 2003
48042003
Intracellular amyloid-β in Alzheimer's disease
FM LaFerla, KN Green, S Oddo
Nature Reviews Neuroscience 8 (7), 499-509, 2007
24972007
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21852019
Intraneuronal Aβ causes the onset of early Alzheimer’s disease-related cognitive deficits in transgenic mice
LM Billings, S Oddo, KN Green, JL McGaugh, FM LaFerla
Neuron 45 (5), 675-688, 2005
15892005
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
FM LaFerla
Nature Reviews Neuroscience 3 (11), 862-872, 2002
12562002
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease
S Oddo, A Caccamo, M Kitazawa, BP Tseng, FM LaFerla
Neurobiology of aging 24 (8), 1063-1070, 2003
12402003
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease
M Blurton-Jones, M Kitazawa, H Martinez-Coria, NA Castello, FJ Müller, ...
Proceedings of the National Academy of Sciences 106 (32), 13594-13599, 2009
10172009
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
S Oddo, L Billings, JP Kesslak, DH Cribbs, FM LaFerla
Neuron 43 (3), 321-332, 2004
10162004
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
9022017
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
M Kitazawa, S Oddo, TR Yamasaki, KN Green, FM LaFerla
Journal of Neuroscience 25 (39), 8843-8853, 2005
7922005
Glucocorticoids increase amyloid-β and tau pathology in a mouse model of Alzheimer’s disease
KN Green, LM Billings, B Roozendaal, JL McGaugh, FM LaFerla
Journal of Neuroscience 26 (35), 9047-9056, 2006
7212006
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
RA Rissman, WW Poon, M Blurton-Jones, S Oddo, R Torp, MP Vitek, ...
The Journal of clinical investigation 114 (1), 121-130, 2004
6812004
The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice
FM LaFerla, BT Tinkle, CJ Bieberich, CC Haudenschild, G Jay
Nature genetics 9 (1), 21-30, 1995
6491995
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
VKM Halagappa, Z Guo, M Pearson, Y Matsuoka, RG Cutler, FM LaFerla, ...
Neurobiology of disease 26 (1), 212-220, 2007
6332007
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
M Fuhrmann, T Bittner, CKE Jung, S Burgold, RM Page, G Mitteregger, ...
Nature neuroscience 13 (4), 411-413, 2010
6242010
Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders
MP Mattson, FM LaFerla, SL Chan, MA Leissring, PN Shepel, JD Geiger
Trends in neurosciences 23 (5), 222-229, 2000
6152000
Alzheimer's disease: Aβ, tau and synaptic dysfunction
FM LaFerla, S Oddo
Trends in molecular medicine 11 (4), 170-176, 2005
6012005
Synergistic interactions between Aβ, tau, and α-synuclein: acceleration of neuropathology and cognitive decline
LK Clinton, M Blurton-Jones, K Myczek, JQ Trojanowski, FM LaFerla
Journal of Neuroscience 30 (21), 7281-7289, 2010
5892010
Animal models of Alzheimer disease
FM LaFerla, KN Green
Cold Spring Harbor perspectives in medicine 2 (11), a006320, 2012
5442012
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20