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Ian Holmes
Ian Holmes
Professor, Computational Biology and Bioengineering, UC Berkeley
Dirección de correo verificada de berkeley.edu
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ...
nature 447 (7146), 799-816, 2007
59942007
Evolution of genes and genomes on the Drosophila phylogeny
AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ...
Nature 450 (7167), 203-18, 2007
22512007
JBrowse: a next-generation genome browser
ME Skinner, AV Uzilov, LD Stein, CJ Mungall, IH Holmes
Genome research 19 (9), 1630-1638, 2009
8042009
Dirichlet multinomial mixtures: generative models for microbial metagenomics
I Holmes, K Harris, C Quince
PloS one 7 (2), e30126, 2012
7682012
JBrowse: a dynamic web platform for genome visualization and analysis
R Buels, E Yao, CM Diesh, RD Hayes, M Munoz-Torres, G Helt, ...
Genome biology 17, 1-12, 2016
7072016
Fast statistical alignment
RK Bradley, A Roberts, M Smoot, S Juvekar, J Do, C Dewey, I Holmes, ...
PLoS computational biology 5 (5), e1000392, 2009
4022009
Web Apollo: a web-based genomic annotation editing platform
E Lee, GA Helt, JT Reese, MC Munoz-Torres, CP Childers, RM Buels, ...
Genome biology 14, 1-13, 2013
3832013
Haloalkane Dehalogenases:  Structure of a Rhodococcus Enzyme,
J Newman, TS Peat, R Richard, L Kan, PE Swanson, JA Affholter, ...
Biochemistry 38 (49), 16105-16114, 1999
2691999
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
EH Margulies, GM Cooper, G Asimenos, DJ Thomas, CN Dewey, A Siepel, ...
Genome research 17 (6), 760-774, 2007
2482007
Evolutionary HMMs: a Bayesian approach to multiple alignment
I Holmes, WJ Bruno
Bioinformatics 17 (9), 803-820, 2001
2322001
Genome-wide nucleotide-level mammalian ancestor reconstruction
B Paten, J Herrero, S Fitzgerald, K Beal, P Flicek, I Holmes, E Birney
Genome research 18 (11), 1829-1843, 2008
2312008
An empirical codon model for protein sequence evolution
C Kosiol, I Holmes, N Goldman
Molecular biology and evolution 24 (7), 1464-1479, 2007
2182007
Apollo: democratizing genome annotation
NA Dunn, DR Unni, C Diesh, M Munoz-Torres, NL Harris, E Yao, ...
PLoS computational biology 15 (2), e1006790, 2019
1942019
Dynamic programming alignment accuracy
I Holmes, R Durbin
Proceedings of the second annual international conference on Computational …, 1998
1701998
A “long indel” model for evolutionary sequence alignment
I Miklós, GA Lunter, I Holmes
Molecular Biology and Evolution 21 (3), 529-540, 2004
1682004
Accelerated probabilistic inference of RNA structure evolution
I Holmes
BMC bioinformatics 6, 1-22, 2005
1672005
An expectation maximization algorithm for training hidden substitution models
I Holmes, GM Rubin
Journal of molecular biology 317 (5), 753-764, 2002
1282002
Finding regulatory elements using joint likelihoods for sequence and expression profile data.
I Holmes, WJ Bruno
Ismb 8, 202-210, 2000
1242000
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
PC Proud, D Tsitoura, RJ Watson, BY Chua, MJ Aram, KR Bewley, ...
EBioMedicine 63, 2021
862021
AAV ancestral reconstruction library enables selection of broadly infectious viral variants
J Santiago-Ortiz, DS Ojala, O Westesson, JR Weinstein, SY Wong, ...
Gene therapy 22 (12), 934-946, 2015
842015
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Artículos 1–20